Animal models of systemic sclerosis

Current Pharmaceutical Design
Florence MorinFrederic Batteux

Abstract

Systemic sclerosis is a systemic connective tissue disorder characterized by the fibrosis of the skin and certain visceral organs, vasculopathy, and immunological abnormalities. Several genetic and inducible animal models of SSc have been developed and are available for research studies. The purpose of this review is to summarize the various animal models of systemic sclerosis and describe the various contributions of these models in terms of understanding the pathophysiology of the condition and searching for new therapeutic strategies for this incurable disease.

Citations

Dec 24, 2015·International Ophthalmology·Sevinc Sahin AtikServet Akar
Oct 25, 2016·The Journal of Investigative Dermatology·Florence MorinFrédéric Batteux
Sep 11, 2016·The Journal of Immunology : Official Journal of the American Association of Immunologists·Florence MorinFrédéric Batteux

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