Animals have a Plan B: how insects deal with the dual challenge of predators and pathogens.

Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
Shelley A Adamo

Abstract

When animals are faced with a life-threatening challenge, they mount an organism-wide response (i.e. Plan A). For example, both the stress response (i.e. fight-or-flight) and the immune response recruit molecular resources from other body tissues, and induce physiological changes that optimize the body for defense. However, pathogens and predators often co-occur. Animals that can optimize responses for a dual challenge, i.e. simultaneous predator and pathogen attacks, will have a selective advantage. Responses to a combined predator and pathogen attack have not been well studied, but this paper summarizes the existing literature in insects. The response to dual challenges (i.e. Plan B) results in a suite of physiological changes that are different from either the stress response or the immune response, and is not a simple summation of the two. It is also not a straight-forward trade-off of one response against the other. The response to a dual challenge (i.e. Plan B) appears to resolve physiological trade-offs between the stress and immune responses, and reconfigures both responses to provide the best overall defense. However, the dual response appears to be more costly than either response occurring singly, resulting in greate...Continue Reading

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Citations

Sep 13, 2020·The Journal of Experimental Biology·Andrew Z Wang, Jerry F Husak
Jan 29, 2021·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Shelley A Adamo

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