Abstract
Atrial fibrillation (AF) is the most common chronic arrhythmia, with increasing healthcare and economic burden and a prevalence which increases with progressive ageing. This study aims to describe overall annual costs per patient for management of non-valvular AF in a primary healthcare (PHC) setting and compare these costs between the groups of patients treated with vitamin K antagonists, antiplatelets or non-treated through a population-based study conducted with electronic health records. We analysed annual costs per person of 19,787 patients in 2012; PHC visits, hospital admissions, AF-related events requiring hospital admission, referrals to secondary specialists, sick leave, diagnostic tests and laboratory tests at PHC level, including INR determinations performed in PHC, and drug therapy. Higher costs of AF management were associated with increasing age, male sex, stroke and bleeding risks, comorbidities and occurrence of events associated to AF. The sensitivity analyses conducted showed that PHC visits and hospitalizations represented the most important part of overall costs for all patients.
References
Jan 21, 2006·Journal of Evaluation in Clinical Practice·Susanna DoddPaula Williamson
Mar 11, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Anna RingborgHarry J G M Crijns
Apr 26, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·A-B WiréhnJ Carstensen
Feb 28, 2009·Women's Health·Janet W Rich-Edwards
Aug 31, 2010·European Heart Journal·A John CammFrans H Rutten
Nov 1, 2011·Revista Española De Cardiología·Rafel RamosMiquel Quesada
Nov 8, 2011·Revista Española De Cardiología·Vivencio BarriosUNKNOWN Primary Care Group in the Clinical Cardiology Section of the Spanish Society of Cardiology
Dec 15, 2011·Lancet·Gregory Y H LipDeirdre A Lane
Mar 27, 2012·Medicina clínica·Bonaventura BolíbarUNKNOWN Grupo SIDIAP
Sep 11, 2012·Revista Española De Cardiología·José R González-JuanateyVirginia Becerra
Mar 23, 2013·BMC Public Health·Concepción ViolánMiguel Ángel Muñoz-Pérez
Apr 4, 2013·Stroke; a Journal of Cerebral Circulation·Amanda R HarringtonDaniel C Malone
Jun 26, 2013·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Doug CoyleGeorge A Wells
Apr 10, 2014·PharmacoEconomics·Torbjørn WisløffMarianne Klemp
Nov 7, 2015·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Manel Mata-CasesBonaventura Bolíbar
Jan 30, 2016·BMJ Open·Maria Giner-SorianoConcepció Violan
Apr 23, 2016·Stroke; a Journal of Cerebral Circulation·Anuj ShahBradley C Martin
Oct 7, 2016·BMJ Open·Manel Mata-CasesDídac Mauricio
Nov 22, 2016·Pharmacoepidemiology and Drug Safety·Maria Giner-SorianoRosa Morros
Mar 28, 2017·Clinical Therapeutics·Jetty A OverbeekRon M C Herings
Feb 7, 2018·BMC Health Services Research·Lionel ChokReto A Schuepbach
Apr 25, 2018·Journal of the Academy of Nutrition and Dietetics·Sissi Stove LorentzenLene Thoresen
Dec 21, 2018·Journal of Medical Internet Research·Brian McMillanDavid Dickinson