Anodal transcranial direct current stimulation of the right dorsolateral prefrontal cortex impairs long-term retention of reencountered memories

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Miklós MariánMihály Racsmány

Abstract

Repeated encounter with encoded memories is often a fundamental component of long-term learning processes, however, the role of repeated access to encoded memories in long-term consolidation is yet to be clarified. Here we investigated whether the long-term retention of newly acquired associative memories is affected if one of the central areas of the attentional control network is stimulated before or after repeated access to acquired information. Non-clinical participants (undergraduate students, N = 118) were exposed to an associative verbal learning task. Following the initial learning of word pairs, memories for the word pairs were reencountered either by re-presenting the stimuli to the participants for restudying or by cued recall. The reencounter phase was either preceded by (Experiment 1) or followed by (Experiment 2) anodal transcranial Direct Current Stimulation of the right dorsolateral prefrontal cortex. Memory retention was assessed seven days after the reencounter phase. When we measured successful access to learned paired-associates in the reencounter phase, there was no difference between the anodal and sham stimulation condition in either Experiment 1 or 2. However, and importantly, anodal stimulation had a de...Continue Reading

References

Mar 15, 1994·Proceedings of the National Academy of Sciences of the United States of America·E TulvingS Houle
Jul 1, 1997·Brain : a Journal of Neurology·A R BraunP Herscovitch
Jul 29, 1998·Brain : a Journal of Neurology·P C FletcherR J Dolan
Jul 29, 1998·Brain : a Journal of Neurology·P C FletcherR J Dolan
Apr 11, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alberto Priori
Jun 14, 2003·Trends in Cognitive Sciences·Reza HabibEndel Tulving
Aug 2, 2003·Nature Reviews. Neuroscience·Jon S Simons, Hugo J Spiers
Sep 10, 2003·Trends in Cognitive Sciences·Clayton E. Curtis, Mark D'Esposito
Jun 1, 1962·Experimental Neurology·O D CREUTZFELDTH KAPP
Dec 4, 2004·Learning & Memory·Ken A Paller, Joel L Voss
Dec 17, 2004·Journal of Cognitive Neuroscience·Brian LevineAnthony R McIntosh
Jul 7, 2005·Experimental Brain Research·Felipe FregniAlvaro Pascual-Leone
Nov 11, 2005·PLoS Biology·Matthew W Jones, Matthew A Wilson
Jun 15, 2007·Nature Neuroscience·Brice A KuhlAnthony D Wagner
Jul 6, 2007·Nature Clinical Practice. Neurology·Felipe Fregni, Alvaro Pascual-Leone
Sep 13, 2007·Learning & Memory·C Brock Kirwan, Craig E L Stark
Feb 16, 2008·Science·Jeffrey D Karpicke, Henry L Roediger
Apr 24, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Charlotte J StaggHeidi Johansen-Berg
Jun 16, 2009·Nature Neuroscience·Mattias P Karlsson, Loren M Frank
Jan 1, 2010·Restorative Neurology and Neuroscience·Eun Kyoung KangNam-Jong Paik
Jan 5, 2010·Nature Reviews. Neuroscience·Susanne Diekelmann, Jan Born
Feb 12, 2010·Journal of Cognitive Neuroscience·Robert S BlumenfeldCharan Ranganath
Jul 20, 2010·Nature Neuroscience·David DupretJozsef Csicsvari
Oct 19, 2010·Trends in Cognitive Sciences·Henry L Roediger, Andrew C Butler
Oct 4, 2011·Brain Stimulation·Amir Homayoun JavadiVincent Walsh
May 5, 2012·Science·Shantanu P JadhavLoren M Frank
Jul 14, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Aron K BarbeyJordan Grafman
Aug 21, 2012·Learning & Memory·Pascale Gisquet-Verrier, David C Riccio
Sep 4, 2012·Nature Neuroscience·Daniel Bendor, Matthew A Wilson
Nov 10, 2012·Brain Stimulation·Amir Homayoun Javadi, Paul Cheng

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