Anogenital Human Papillomavirus and HIV Infection in Rwandan Men Who Have Sex With Men.

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Gad MurenziJ Palefsky

Abstract

Men who have sex with men (MSM) have a high prevalence of anal and penile human papillomavirus (HPV) infections with MSM living with HIV (MSMLH) bearing the highest rates. Data on anogenital high-risk HPV (hrHPV) among MSM in Rwanda and the associated risk factors are scant. We recruited 350 self-identified MSM aged 18 years living in Kigali, Rwanda, with 300 recruited from the community and 50 from partner clinics. Anal and penile specimens from all participants were analyzed for hrHPV using the AmpFire platform. Logistic regression was used to calculate crude odds ratios (ORs) and adjusted ORs (aORs) with 95% confidence intervals (95% CIs) as a measure of association between various factors and anal and penile hrHPV infection prevalence. Anal hrHPV prevalence was 20.1%, was positively associated with having receptive anal sex with more partners (aOR: 9.21, 95% CI: 3.66 to 23.14), and was negatively associated with having insertive anal sex with more partners (aOR: 0.28, 95% CI: 0.12 to 0.66). Penile hrHPV prevalence was 35.0%, was negatively associated with having receptive anal sex with more partners (aOR: 0.29, 95% CI: 0.13 to 0.66), and differed significantly by HIV status, with 55.2% and 29.7% for MSMLH and HIV-negative M...Continue Reading

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Citations

Feb 20, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Issifou YayaChristian Laurent
Jan 16, 2021·The Journal of the Association of Nurses in AIDS Care : JANAC·Athanase MunyanezaViraj V Patel

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Methods Mentioned

BETA
Genotyping
Assay
circumcision

Software Mentioned

SAS

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