Anomalous self-experiences and their relationship with symptoms, neuro-cognition, and functioning in at-risk adolescents and young adults

Comprehensive Psychiatry
Anna ComparelliPaolo Girardi

Abstract

Empirical and theoretical studies support the notion that anomalous self-experience (ASE) may constitute a phenotypic aspect of vulnerability to schizophrenia, but there are no studies examining the relationship of ASE with other clinical risk factors in a sample of ultra-high risk (UHR) subjects. The aim of the present study was to explore the relationship between ASE, prodromal symptoms, neurocognition, and global functioning in a sample of 45 UHR adolescents and young adults (age range 15-25years) at first contact with Public Mental Health Services. Prodromal symptoms and global functioning were assessed through the SIPS interview. ASE was evaluated through the Examination of Anomalous Self-Experience (EASE); for neurocognition, we utilized a battery of tests examining seven cognitive domains as recommended by the Measurement And Treatment Research to Improve Cognition in Schizophrenia. In the UHR group, higher levels in two domains of the EASE (stream of consciousness and self-awareness) were found in comparison with help-seeking subjects. Correlational analysis corrected for possible confounding variables showed a strong association (p>0.001) between higher EASE scores and global functioning. A principal factor analysis wi...Continue Reading

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Citations

Jul 18, 2016·Comprehensive Psychiatry·Marco GarzittoPaolo Brambilla
Nov 23, 2020·European Archives of Psychiatry and Clinical Neuroscience·Marta Hernández-GarcíaVicente Molina
Feb 10, 2021·Early Intervention in Psychiatry·Hadar HazanRichard J Linscott
Feb 17, 2021·Early Intervention in Psychiatry·Meng SunLiang Zhou
Jan 25, 2020·Schizophrenia Research·David C CiceroBarnaby Nelson
Apr 16, 2021·Frontiers in Psychiatry·Renata Pionke-UbychŁukasz Gawęda
Nov 17, 2021·European Archives of Psychiatry and Clinical Neuroscience·Tor Gunnar VærnesPaul Møller

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