Anorectal manometry with and without ketamine for evaluation of defecation disorders in children

Journal of Pediatric Surgery
A S KeshtgarG S Clayden

Abstract

Anorectal manometry (ARCM) provides valuable information in children with chronic constipation and fecal incontinence but may not be tolerated in the awake child. This study aimed to evaluate the effect of ketamine anesthesia on the assessment of anorectal function by manometry and to evaluate defecation dynamics and anal sphincter resting pressure in the context of pathophysiology of chronic functional (idiopathic) constipation and soiling in children. This was a prospective study of children who were investigated for symptoms of chronic constipation and soiling between April 2001 and April 2004. We studied 52 consecutive children who had awake ARCM, biofeedback training and endosonography (awake group) and 64 children who had ketamine anesthesia for ARCM and endosonography (ketamine group). We age matched 31 children who had awake anorectal studies with 27 who had ketamine anesthesia. The children in awake and ketamine groups were comparable for age, duration of bowel symptoms and duration of laxative treatments. ARCM profile was comparable between the awake and the ketamine groups with regard to anal sphincter resting pressure, rectal capacity, amplitude of rectal contractions, frequency of rectal and IAS contractions and fu...Continue Reading

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Citations

Oct 11, 2016·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·L RodriguezM Saps
Sep 15, 2016·Journal of Pediatric Surgery·Kristiina KyrklundRisto J Rintala
Jan 29, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Eleni AthanasakosMohamed Mutalib
Feb 5, 2019·International Journal of Pediatrics·Katherine LamparykRita Steffen
Oct 30, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Gregory YatesEleni Athanasakos
Sep 4, 2021·Journal of Pediatric Gastroenterology and Nutrition·Ricardo A ArbizuSamuel Nurko

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