PMID: 9416821Jan 7, 1998Paper

Anosognosia: examining the disconnection hypothesis

Journal of Neurology, Neurosurgery, and Psychiatry
J C AdairK M Heilman

Abstract

To test the hypothesis that anosognosia for hemiparesis results from intrahemispheric disconnection. Using right carotid barbiturate injection as a model for anosognosia for hemiparesis, systematic attempts were made to modify deficit awareness by providing the left hemisphere with explicit information regarding left upper extremity function. Experimental interventions failed to modify deficit awareness in 19 of 32 patients. In those patients who discovered their weakness, attempted movement of the weak limb seems more important than explicit observation of the extremity by the left hemisphere. The results fail to support Geschwind's disconnection hypothesis for anosognosia for hemiparesis.

Citations

Sep 25, 2008·Experimental Brain Research·Giuseppe Vallar, Roberta Ronchi
Jul 14, 2009·Experimental Brain Research·Paul Mark Jenkinson, Aikaterini Fotopoulou
Apr 7, 2006·Journal of Neurology·Catarina O SantosM Luísa Figueira
Sep 5, 2002·Neuropsychologia·Gianna CocchiniSergio Della Sala
Sep 23, 2011·Journal of Clinical and Experimental Neuropsychology·Paul M JenkinsonSimon J Ellis
Sep 25, 2008·Brain : a Journal of Neurology·Aikaterini FotopoulouMichael Kopelman
Jan 18, 2002·Current Opinion in Neurology·Antonio CarotaJulien Bogousslavsky
Dec 6, 2008·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Karen G Langer, Mark C Samuels
Dec 17, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·K M HeilmanJ C Adair
Jan 1, 2009·Neurology International·Kazuo AbeYutaka Uchida
Jun 25, 2014·Schizophrenia Research·Kelly Rowe BijankiNancy C Andreasen
Dec 8, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Martina GandolaGabriella Bottini
Jul 16, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Kenneth M Heilman
Feb 7, 2009·Consciousness and Cognition·Paul M JenkinsonSimon J Ellis
Aug 17, 2006·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jonathan Graff-RadfordKenneth M Heilman
Nov 30, 2007·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Kenneth M Heilman

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