PMID: 38192Jun 1, 1979

Antacids and peptic ulcer--a reappraisal

T Morris, J Rhodes


Antacids can reduce gastroduodenal acidity for long periods if taken in substantial quantities after food. Their healing effect on gastric ulcer is minimal, if present at all, and easily overwhelmed by the benefit obtained from admission to hospital. Intensive antacid therapy appears effective in healing duodenal ulcer and preventing haemorrhage from stress ulcer, and is comparable in these respects with cimetidine but with a higher incidence of side-effects. Clinical impression strongly suggests that antacids relieve pain in peptic ulcer but objective confirmation is lacking.


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Related Concepts

Gastric Juice
Hemorrhagic Septicemia
Gastric Ulcer
Marginal Ulcer
Duodenal Ulcer
Clinical Trials
Peptic Ulcer Hemorrhage

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