PMID: 2500473Jul 1, 1989Paper

Antecedent angina: a predictor of residual stenosis after thrombolytic therapy

Journal of the American College of Cardiology
B A BergelsonD P Faxon

Abstract

Patients with a significant residual stenosis after thrombolytic therapy are believed by many to be at increased risk for repeat ischemic events and may be candidates for prompt angiography and revascularization. To test the hypothesis that patients with antecedent angina (Canadian classes I to IV, greater than or equal to 24 h before myocardial infarction) are more likely to have a significant residual stenosis (greater than or equal to 60% diameter reduction) than are those without antecedent angina, the coronary angiograms of 82 consecutive patients undergoing routine angiography after thrombolytic therapy were reviewed. Compared with the patients without antecedent angina, the group with antecedent angina had an increased mean stenosis (74% versus 58%) and more multivessel disease (44% versus 5%). The sensitivity and specificity of a clinical history of antecedent angina predicting the presence of a significant residual stenosis were 75% and 96%, respectively; the positive predictive accuracy was 98%. These data suggest that antecedent angina can be used to identify a high risk subgroup whose condition may warrant routine coronary angiography.

References

Apr 1, 1988·The American Journal of Cardiology·K P RentropM Van Buskirk
May 1, 1988·Journal of the American College of Cardiology·D W MyearsS R Bergmann
May 1, 1988·The American Journal of Cardiology·L A PierardH E Kulbertus
Jun 16, 1988·The New England Journal of Medicine·V J Marder, S Sherry
Feb 1, 1987·British Heart Journal·M FujitaH Asanoi
Oct 1, 1969·Circulation·H A SolomonT Killip

❮ Previous
Next ❯

Citations

Mar 1, 1991·Clinical Cardiology·B FujiiS Iwamoto
Apr 1, 1992·Clinical Cardiology·L A PiérardH E Kulbertus
May 15, 1995·The American Journal of Cardiology·D G RizikT L Schreiber
Dec 24, 1997·Australian and New Zealand Journal of Medicine·G D Kerr, D R Dunt

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.