PMID: 2143644Jul 1, 1990Paper

Antenatal diagnosis of abdominal wall defects: a missed opportunity?

Archives of Disease in Childhood
J P Roberts, D M Burge


A review of six years' experience with antenatal diagnosis of abdominal wall defects by ultrasound showed its impact to be limited by poor detection rates. Twenty infants with exomphalos and 20 with gastroschisis were recorded but only 25 (63%) were diagnosed antenatally. The ultrasound false negative rate was higher for exomphalos (35%) than for gastroschisis (22%). No difference was detected in the incidence of associated abnormalities, premature gestation, primary closure rate, or mortality between the antenatally and postnatally diagnosed groups for either exomphalos or gastroschisis. Antenatal diagnosis of gastroschisis has little effect on management but allows parental counselling and in utero transfer. The frequency of concomitant abnormalities in exomphalos profoundly affects prognosis and the detection of these is the major role of antenatal diagnosis in this condition. Failure to detect abdominal wall defects by ultrasound may be a reflection of technique or equipment, but some gastroschisis may be of perinatal onset and not detectable antenatally.


Nov 1, 1985·Prenatal Diagnosis·L B NielsenB Nørgaard-Pedersen
Oct 1, 1987·Prenatal Diagnosis·P D Knott, N V Colley
Aug 1, 1985·Journal of Pediatric Surgery·M B HershensonC E Hunt
Feb 1, 1987·American Journal of Obstetrics and Gynecology·M SermerM Skidmore
Jan 1, 1985·British Journal of Obstetrics and Gynaecology·D H RedfordM J Whittle
Aug 1, 1984·Journal of Pediatric Surgery·D K NakayamaA A de Lorimier
Sep 1, 1984·Prenatal Diagnosis·J M DavidsonB H Thompson

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Feb 1, 1997·Pediatric Radiology·W H RamsdenD Martinez
May 18, 1994·European Journal of Obstetrics, Gynecology, and Reproductive Biology·P PoulainJ R Giraud
Aug 1, 1993·Trends in Biochemical Sciences·R GrabowskiW Buckel
Apr 1, 1996·Journal of Pediatric Surgery·R FisherE Dykes
Nov 1, 1992·British Journal of Obstetrics and Gynaecology·R A CrawfordC H Rodeck
Jun 1, 1996·The Australian and New Zealand Journal of Surgery·E A NichollsC Hayward
Oct 20, 2005·Acta Obstetricia Et Gynecologica Scandinavica·Jakob Nakling, Bjørn Backe
Jul 21, 1998·Annals of the New York Academy of Sciences·D Biarent

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