PMID: 9166326May 1, 1997Paper

Antepartum fetal cerebral hemorrhage not predicted by current surveillance methods in cholestasis of pregnancy

Obstetrics and Gynecology
A MatosB Patrício

Abstract

The reason for increased fetal mortality in cholestasis of pregnancy is not completely understood. Intracerebral hemorrhage due to coagulation disorders, similar to those reported in the mother, is a possible explanation. Antepartum fetal death occurred at 37 weeks in a primigravida with cholestasis of pregnancy. The woman was taking no medication. Autopsy revealed extensive cerebral hemorrhage. A cardiotocogram and biophysical profile performed 24 hours and 5 days, respectively, before fetal death had been normal. Antepartum fetal death may occur in patients with mild cholestasis who are taking no medication. Intracerebral hemorrhage is a possible cause, and this may be unpredictable with current methods of fetal surveillance. This possibility constitutes an argument in support of delivering these pregnancies as soon as lung maturity is achieved.

References

Apr 10, 1976·British Medical Journal·R ReidB Storey
Nov 1, 1988·British Journal of Obstetrics and Gynaecology·N M Fisk, G N Storey
Aug 1, 1988·The Australian & New Zealand Journal of Obstetrics & Gynaecology·N M FiskG N Storey

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Citations

Dec 26, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Nadia RoncagliaAlessandro Ghidini
Mar 16, 2001·The Journal of Perinatal & Neonatal Nursing·D G Palmer, J Eads
Feb 4, 2010·Current Opinion in Obstetrics & Gynecology·João Bernardes, Diogo Ayres-de-Campos
May 7, 2009·World Journal of Gastroenterology : WJG·Victoria Geenes, Catherine Williamson
May 16, 2015·Food Chemistry·Sharlene M O BritoIrwin R A Menezes
May 23, 2017·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Giulianna Echeverria MacedoThaís Posser
Jul 16, 1999·The American Journal of Gastroenterology·C A Riely
Oct 25, 2012·Natural Product Research·Nerilson M LimaCecilia V Nunez
Jun 16, 2011·Phytotherapy Research : PTR·L R BonjardimM A Botelho
Mar 15, 2003·Gastroenterology Clinics of North America·Bimaljit S Sandhu, Arun J Sanyal
Apr 9, 2001·Clinics in Liver Disease·E A Fagan
Jun 25, 1998·Seminars in Perinatology·K M Davidson
Aug 6, 2010·Obstetrics and Gynecology Clinics of North America·Bhuvan PathakRichard H Lee

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