PMID: 9185037Jun 1, 1997Paper

Anterior chamber angles shallowing and intraocular pressure after topical pilocarpine

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
C C YangC B Tsai

Abstract

Pilocarpine has been well recognized as the drug of choice for acute angle-closure glaucoma. The purpose of this study is to clarify quantitatively the change of anterior chamber angle and depth with the passage of time after pilocarpine drop administration. Chamber angles of the four quadrants and chamber depths were measured in 18 normal subjects by Scheimpflug Video Image prior to and 30, 60, and 180 minutes after administration of one drop of 4% pilocarpine in one eye, while the opposite eye served as control. The anterior chamber angle and depth showed a significant shallowing at 30, 60 and 180 minutes after 4% pilocarpine administration with a maximal effect of -3.61 degrees and -0.15 mm at 30 minutes, respectively, while the reduction of intraocular pressure reached its maximal effect at 180 minutes. These facts should be well understood in the treatment of angle-closure glaucoma.

References

Feb 1, 1990·Ophthalmology·C J PavlinF S Foster
Jan 1, 1990·Ophthalmic Research·K SasakiY Emori
Jan 1, 1990·Ophthalmic Research·T ShibataN Takahashi
Dec 1, 1974·Archives of Ophthalmology·D H AbramsonM E Smith
Jan 1, 1974·The British Journal of Ophthalmology·R Mapstone
May 1, 1954·American Journal of Ophthalmology·O BARKAN

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Citations

Feb 15, 2000·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·P T HungT Wei
May 27, 2008·Survey of Ophthalmology·David S Friedman, Mingguang He
Dec 12, 2012·Veterinary Ophthalmology·Susan TsaiMichael R Robinson
Feb 27, 2021·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Paul M KarpeckiJay S Pepose
Sep 10, 2019·Journal of Current Glaucoma Practice·Ardiella YunardJoedo Prihartono

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