Anterior cingulate cortex and conflict detection: an update of theory and data

Cognitive, Affective & Behavioral Neuroscience
Cameron S Carter, Vincent van Veen

Abstract

The dorsal anterior cingulate cortex (ACC) and associated regions of the medial frontal wall have often been hypothesized to play an important role in cognitive control. We have proposed that the ACC's specific role in cognitive control is to detect conflict between simultaneously active, competing representations and to engage the dorsolateral prefrontal cortex (DLPFC) to resolve such conflict. Here we review some of the evidence supporting this theory, from event-related potential (ERP) and fMRI studies. We focus on data obtained from interference tasks, such as the Stroop task, and review the evidence that trial-to-trial changes in control engagement can be understood as driven by conflict detection; the data suggest that levels of activation of the ACC and the DLPFC in such tasks do indeed reflect conflict and control, respectively. We also discuss some discrepant results in the literature that highlight the need for future research.

Citations

Jan 7, 2009·Archives of General Psychiatry·Rachel MarshBradley S Peterson
Jul 3, 2013·Psychopharmacology·Ksenija MarinkovicAdrian K C Lee
Oct 12, 2010·European Archives of Psychiatry and Clinical Neuroscience·Krystyna A MathiakKlaus Mathiak
Nov 22, 2008·Psychological Research·Matthew M Botvinick, Zev B Rosen
Nov 6, 2010·Psychological Research·Ulrich AnsorgeWilfried Kunde
Apr 15, 2011·Journal of Inherited Metabolic Disease·Benedikt SundermannReinhold Feldmann
May 5, 2012·Brain Imaging and Behavior·Michael C StevensSuzanne T Witt
Jun 8, 2012·Brain Imaging and Behavior·Andrew R MayerKasra Mojtahed
Mar 17, 2012·Integrative Psychological & Behavioral Science·Mehmet Emin Ceylan, Aslıhan Sayın
Mar 5, 2013·Behavioural Brain Research·Aldis P Weible
Mar 23, 2013·Behavioural Brain Research·Ling XiangQinglin Zhang
Sep 22, 2009·Journal of the International Neuropsychological Society : JINS·Michael J LarsonWilliam M Perlstein
Jan 26, 2012·Journal of the International Neuropsychological Society : JINS·Michael J LarsonThomas J Farrer
Jun 9, 2009·Nature Neuroscience·Frédérique KouneiherEtienne Koechlin
May 6, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·John D BeaverPaul M Matthews
Jan 21, 2009·Nature Reviews. Neuroscience·Farshad A MansouriMark J Buckley
Oct 21, 2011·Nature Reviews. Neuroscience·Rita Z Goldstein, Nora D Volkow
Aug 20, 2011·The Quarterly Journal of Experimental Psychology : QJEP·Nash UnsworthGene A Brewer
Feb 2, 2012·Social Neuroscience·Griet EmondsPaul M Parizel
Jan 31, 2013·Social Neuroscience·Claudia BrunnliebMarcus Heldmann
May 7, 2010·Developmental Neuropsychology·Elisabeth A WildeHarvey S Levin
Jun 14, 2008·Brain : a Journal of Neurology·Katharine N ThakkarDara S Manoach
Aug 12, 2010·Cerebral Cortex·Todd A Kelley, Nilli Lavie
Mar 15, 2012·Cerebral Cortex·Felix HoffstaedterSimon B Eickhoff
Jun 5, 2012·Cerebral Cortex·Guillaume BarbalatSarah-Jayne Blakemore
May 28, 2010·Social Cognitive and Affective Neuroscience·Simone KühnRick B van Baaren
May 26, 2011·Social Cognitive and Affective Neuroscience·Anett GyurakÖzlem N Ayduk
Oct 19, 2011·Social Cognitive and Affective Neuroscience·Ning MaWim Fias
Dec 14, 2011·Social Cognitive and Affective Neuroscience·Kathleen ThomaesDick J Veltman
Mar 6, 2013·Social Cognitive and Affective Neuroscience·Leonie KobanPatrik Vuilleumier
Apr 12, 2013·Social Cognitive and Affective Neuroscience·Veronika I MüllerSimon B Eickhoff
Nov 18, 2008·Schizophrenia Bulletin·Deanna M BarchTrevor W Robbins
Apr 7, 2010·Schizophrenia Bulletin·Kathrin KochRalf G M Schlösser
Nov 25, 2011·Schizophrenia Bulletin·Cameron S CarterAngus Macdonald
Jan 18, 2014·Learning & Memory·Andrew J D NelsonJohn P Aggleton

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