Anterior cruciate ligament deficiency causes brain plasticity: a functional MRI study

The American Journal of Sports Medicine
Eleni KapreliStefan Sunaert

Abstract

The mechanoreceptors located in anterior cruciate ligament (ACL) constitute an afferent source of information toward the central nervous system. It has been proposed that ACL deficiency causes a disturbance in neuromuscular control, affects central programs and consequently the motor response resulting in serious dysfunction of the injured limb. The objective of this study was to investigate whether chronic anterior cruciate ligament injury causes plastic changes in brain activation patterns. Case control study; Level of evidence, 3. Seventeen right leg-dominant male participants with chronic anterior cruciate ligament deficiency and 18 matched healthy male participants with no special sport or habitual physical activity participated in this study. Patient selection criteria comprised a complete right unilateral anterior cruciate ligament rupture > or = 6 months before testing. Brain activation was examined by using functional magnetic resonance imaging technique (1.5-T scanner). Results show that patients with anterior cruciate ligament deficiency had diminished activation in several sensorimotor cortical areas and increased activation in 3 areas compared with controls: presupplementary motor area, posterior secondary somatose...Continue Reading

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Methods Mentioned

BETA
amputation
cochlear implants
amputations

Software Mentioned

MATLAB
SPSS
Presentation
SPM99
MarsBaR SPM

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