Anterior pelvic exenteration with total vaginectomy for recurrent or persistent genitourinary malignancies: review of surgical technique, complications, and outcome

Gynecologic Oncology
V AndikyanD S Chi

Abstract

To describe the surgical technique, complications, and outcomes after anterior pelvic exenteration with total vaginectomy (AETV) for recurrent or persistent genitourinary malignancies. We reviewed the medical records of all patients who underwent AETV between 12/2002 and 07/2011. Relevant demographic, clinical, and pathological information was collected. Postoperative complications and rates of readmission and reoperation (up to 180 days after surgery) were examined, and preliminary survival data were obtained. We identified 11 patients who underwent AETV. The median age at the time of the surgery was 55 years (range, 36-71). The median tumor size was 0.9 cm (range, microscopic - 4). Primary tumor sites included: cervix, 6; uterus, 3; vagina, 1; and urethra, 1. Complete surgical resection with negative pathologic margins was achieved in all 11 patients. Major postoperative complications occurred in 4 patients (36%). Six patients (55%) required readmission to the hospital. No operative mortalities were observed, and none of the patients required a re-operation. With a median follow-up after the procedure of 25 months (range, 6-95), none of the patients developed a pelvic recurrence. Ten patients (91%) were alive without evidence...Continue Reading

References

Dec 1, 1989·Obstetrics and Gynecology·G W MorleyJ A Roberts
Jul 1, 1995·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·H T NgC C Yuan
Apr 9, 2005·Surgical Oncology Clinics of North America·Nicholas C LambrouHervy E Averette
May 13, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M Höckel

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Citations

Jun 3, 2015·Gynecologic Oncology·Floor J Backes, Douglas D Martin
Aug 6, 2015·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Paola ArnaboldiGabriella Pravettoni
Nov 22, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Hebert Alberto VargasHedvig Hricak
Jul 23, 2014·Current Opinion in Oncology·Manpreet KaurIgnace Vergote
May 9, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Anna GermanovaDavid Cibula
Aug 27, 2021·Experimental and Therapeutic Medicine·Mihai GheorgheAndreea Anamaria Moldovan

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