Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome.

Indian Journal of Ophthalmology
Jyotirmay Biswas, Sridharan Sudharshan

Abstract

Ocular complications are known to occur as a result of human immunodeficiency virus (HIV) disease. They can be severe leading to ocular morbidity and visual handicap. Cytomegalovirus (CMV) retinitis is the commonest ocular opportunistic infection seen in acquired immune deficiency syndrome (AIDS). Though posterior segment lesions can be more vision-threatening, there are varied anterior segment manifestations which can also lead to ocular morbidity and more so can affect the quality of life of a HIV-positive person. Effective antiretroviral therapy and improved prophylaxis and treatment of opportunistic infections have led to an increase in the survival of an individual afflicted with AIDS. This in turn has led to an increase in the prevalence of anterior segment and adnexal disorders. Common lesions include relatively benign conditions such as blepharitis and dry eye, to infections such as herpes zoster ophthalmicus and molluscum contagiosum and malignancies such as squamous cell carcinoma and Kaposi's sarcoma. With the advent of highly active antiretroviral therapy, a new phenomenon known as immune recovery uveitis which presents with increased inflammation, has been noted to be on the rise. Several drugs used in the manageme...Continue Reading

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Citations

Oct 10, 2013·Indian Journal of Ophthalmology·Bipasha MukherjeeJyotirmay Biswas
Aug 20, 2008·Indian Journal of Ophthalmology·Rajeev Soman
Jun 25, 2014·Indian Journal of Sexually Transmitted Diseases and AIDS·Priti Kapadia GuptaKunjan J Patel
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Methods Mentioned

BETA
PCR
scrapings
biopsies
electron microscopy
biopsy

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