Anterior segment optical coherence tomography in congenital corneal opacities

Ophthalmology
Anna S MajanderKari Krootila

Abstract

To evaluate the clinical usefulness of anterior segment (AS) optical coherence tomography (OCT) in diagnosis and follow-up of children with congenital corneal opacities. Noncomparative case series. Seven consecutive patients with bilateral congenital corneal opacity between 2 days and 2.5 years of age. In addition to basic outpatient examination, eyes were imaged using AS OCT. Anterior segment structures and corneal thicknesses were evaluated from the images. Three children also underwent evaluation under anesthesia, including measurement of corneal thickness with ultrasound pachymetry. Evaluation of the type and severity of the congenital corneal opacity based on the findings in AS OCT. Thirteen of the 14 eyes could be imaged using AS OCT. The youngest patient studied was only 2 days old. Three distinct phenotypes were found based on the AS OCT findings. Three patients with iridocorneal adhesions were deduced to have type 1 Peters' anomaly, and 2 patients with lenticulocorneal adhesions were deduced to have type 2 Peters' anomaly. The 2 youngest patients had complete corneal opacity with features of corneal staphyloma and marked changes in the AS structures during the first months of life. Anterior segment OCT was a valuable m...Continue Reading

References

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Citations

Apr 4, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yureeda QaziPedram Hamrah
Dec 26, 2015·Journal of Cataract and Refractive Surgery·Joshua H HouJose de la Cruz
Oct 4, 2015·Journal of Cataract and Refractive Surgery·Matthew NguyenScott R Lambert
Apr 12, 2016·Acta Ophthalmologica·Anna S MajanderKari Krootila
Jun 22, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·S SiebelmannClaus Cursiefen
Sep 24, 2016·The British Journal of Ophthalmology·Jiaxu HongJianjiang Xu
Aug 13, 2014·Acta Ophthalmologica·Elina Rantala, Anna S Majander
Apr 25, 2018·BMC Ophthalmology·Yi-Ju HoHung-Chi Chen
Dec 13, 2018·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C ElhardtC Wertheimer

Related Concepts

Cornea
Corneal Opacity
Physiologic Intraocular Pressure
Ophthalmoscopy
Intraocular Pressure Test
Ultrasound Biomicroscopy
Tomography, Optical Coherence
Congenital Abnormality
Tissue Adhesions
Anesthesia Procedures

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