Anterior segment transplantation with a novel biosynthetic graft

Eye & Contact Lens
Soosan JacobAmar Agarwal

Abstract

Staphylectomy with sclerokeratoplasty has been performed in cases with large anterior staphyloma. This report describes a technique using a new biosynthetic graft to simulate the anterior segment in the eye of a 4-month-old child with diffuse anterior staphyloma and cataractous lens with compromised zonules. The graft had a biologic part (corneoscleral button) and a synthetic part (aniridia intraocular lens). Two partial thickness flaps and sclerotomies were made in the graft through which the lens haptics were externalized. After staphylectomy and lensectomy of the host, the graft was sutured. After intrascleral tuck of the lens haptics before fibrin glue-assisted flap closure was then done. On the first postoperative day, the child was following light with the operated eye, and closure of the lids and cosmesis were markedly improved. Between the first and fourth month follow-up, and with the normal eye occluded, the child was following light and reaching out for objects. The cornea was clear with no evidence of rejection or failure. At 5 months, a persistent epithelial defect developed, leading by 6 months into a nebulomacular opacity partially obscuring the pupil. At 6 months, the results of the technique are anatomically an...Continue Reading

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Citations

May 10, 2012·Indian Journal of Ophthalmology·Bhaskar SrinivasanGeetha K Iyer
Oct 20, 2012·Current Opinion in Ophthalmology·Dhivya Ashok Kumar, Amar Agarwal
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Dec 4, 2019·Current Opinion in Ophthalmology·Soosan JacobNaveen K Rao

Related Concepts

Anterior Eyeball Segment Structure
Glutaraldehyde-Stabilized Grafts
Pseudoaphakia
Phakectomy
Corneal Diseases
Sclera
Lamellar Keratoplasty
Intraocular Lens Implantation Procedure
Cornea
Eye

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