Anterior visual pathway gliomas

International Ophthalmology Clinics
C R Thompson, S Lessell

Abstract

The benign anterior visual pathway glioma undoubtedly is the most controversial subject in neuro-ophthalmology. Although we are persuaded by the evidence that they are true neoplasms rather than hamartomas, the controversy over their biological nature seems moot, as they have a low growth potential. That is not to say that serious visual loss is not common or that, in some cases (especially among those lesions arising in the chiasmalhypothalamic region), tumor-related death and disability cannot occur. These posteriorly located lesions may cause hydrocephalus, and shunting is required if that occurs. The need for shunting in such cases may be the only point on which experts agree. What has yet to be established is whether any of the forms of therapy now available for anterior visual pathway gliomas without hydrocephalus is better than no treatment. Surgery, radiation, and chemotherapy all carry risks. A randomized, controlled study, if feasible, would be apt to settle the issue. The low incidence of these tumors might frustrate attempts to complete such an investigation in a reasonable period. A team of physicians should manage patients with benign anterior visual pathway gliomas. Radiologists, neurologists, neurosurgeons, radi...Continue Reading

Citations

Jun 2, 2005·Neuroimaging Clinics of North America·Alfred L WeberNelson R Sabates
Feb 23, 1999·Radiologic Clinics of North America·M D HollanderL M Tartaglino
Aug 21, 2013·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Sarah N Khan, Ali R Sepahdari
Feb 28, 2014·Surgical Neurology International·Poonam BhakerRakesh K Vasishta

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