Anthelminthic resistance of Haemonchus contortus in small ruminants in Switzerland and Southern Germany.

Wiener klinische Wochenschrift
Miriam C ScheuerleKurt Pfister

Abstract

Two goat and two sheep flocks have been found to be suspicious of a clinically evident reduced anthelmintic efficacy, i.e. lacking improvement of gastrointestinal disorders, insufficient weight gain and continuing inappetence after anthelmintic treatments. In order to conduct an appropriate evaluation of the efficacy the following trials were performed: the faecal egg count reduction test on the studied goats of the two herds revealed a reduction of the egg-excretion after the eprinomectin-treatment (1 mg/kg BW, pour-on) of 17.4% and 27.5%, respectively, which clearly confirms the occurrence of anthelmintic resistance against eprinomectin in these two herds. The alternatively administered moxidectin-treatment (1 mg/kg BW, pour-on) of one flock resulted in a 99.1% faecal egg count reduction. In both sheep flocks, 30 randomly selected sheep were divided in three groups and each group was treated with a different anthelmintic, according to the instructions for use. The faecal egg count reductions for the various groups treated orally with benzimidazoles were 70.8% and 55.3% (albendazole), 52.4% (fenbendazole) and 47.3% (oxfendazole). The two moxidectin-treated groups (0.2 mg/kg BW, oral) showed an EpG-reduction of 100% and 44.3%, ...Continue Reading

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Citations

May 17, 2011·Acta Veterinaria Scandinavica·Atle V M DomkeSnorre Stuen
Jun 3, 2014·BMC Veterinary Research·Sergio Aurelio ZanzaniMaria Teresa Manfredi
Jul 31, 2014·Parasite : Journal De La Société Française De Parasitologie·Signe A HolmHeidi L Enemark
Apr 17, 2012·Veterinary Parasitology·E PapadopoulosS Ptochos
Jan 15, 2020·Journal of Veterinary Research·Sergio Aurelio ZanzaniMaria Teresa Manfredi
Mar 6, 2021·BMC Veterinary Research·Jaroslav VadlejchJohannes Charlier
Apr 29, 2021·Acta Veterinaria Scandinavica·Agnė BeleckėSaulius Petkevičius
Sep 21, 2021·Journal of Veterinary Pharmacology and Therapeutics·Dietmar HamelSteffen Rehbein

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Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.