PMID: 525922Aug 1, 1979Paper

Anthelmintic activities of B1a fraction of avermectin against gastrointestinal nematodes in calves

American Journal of Veterinary Research
G W Benz, J V Ernst

Abstract

Anthelmintic activities of the B1a fraction of avermectin were evaluated in a controlled experiment. Twenty 12-week-old calves artificially infected with gastrointestinal nematodes were allotted to four groups. Calves in group 1 were used as nonmedicated controls; other calves in groups 2, 3, and 4 were given (orally) B1a avermectin at dosage levels of 50, 100, and 200 microgram/kg of body weight, respectively. These treatments were given 35 days after calves were inoculated with infective nematode larvae. In groups 2, 3, and 4, overall reductions (based on geometric means) were 98.6%, 98.7%, and 98.4%, respectively. These reductions were highly significantly different (P less than 0.01) from the control calves. Nematodes in the calves were Haemonchus contortus. Ostertagia ostertagi, Trichostrongylus axei, T colubriformis, Cooperia oncophora, C punctata, and Oesophagostomum radiatum.

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Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.