Anthracycline Cardiotoxicity in a Patient with Diffuse Large B-Cell Lymphoma: A Case Report

Curēus
Francisco Teixeira da SilvaManuel Ferreira

Abstract

Cardiotoxicity is a relevant side effect of cancer therapy that leads to increased patient morbidity and mortality. It is fundamental to understand and remember it as a cause of disease since accurate and timely diagnosis is crucial. We present the case of a patient who developed chemotherapy-associated cardiac dysfunction after receiving treatment for a diffuse large B-cell lymphoma. Clinical history, echocardiography, and differential diagnosis led us to attribute her condition to heart failure (HF) due to early doxorubicin-induced cardiomyopathy. The patient outcome was favorable. We discuss the pathogenesis and incidence of anthracycline-induced cardiotoxicity as well as strategies for its detection, prevention, and treatment.

References

Jul 5, 2012·Current Cardiology Reviews·Maria Volkova, Raymond Russell
Jun 4, 2016·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Margarida CruzManuel Campelo
Apr 8, 2020·Frontiers in Cardiovascular Medicine·Daniela CardinaleCarlo Maria Cipolla
Mar 17, 2020·JACC. CardioOncology·Jennifer E Liu

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