Anthropogenic stressors impact fish sensory development and survival via thyroid disruption.

Nature Communications
Marc BessonDavid Lecchini

Abstract

Larval metamorphosis and recruitment represent critical life-history transitions for most teleost fishes. While the detrimental effects of anthropogenic stressors on the behavior and survival of recruiting fishes are well-documented, the physiological mechanisms that underpin these patterns remain unclear. Here, we use pharmacological treatments to highlight the role that thyroid hormones (TH) play in sensory development and determining anti-predator responses in metamorphosing convict surgeonfish, Acanthurus triostegus. We then show that high doses of a physical stressor (increased temperature of +3 °C) and a chemical stressor (the pesticide chlorpyrifos at 30 µg L-1) induced similar defects by decreasing fish TH levels and affecting their sensory development. Stressor-exposed fish experienced higher predation; however, their ability to avoid predation improved when they received supplemental TH. Our results highlight that two different anthropogenic stressors can affect critical developmental and ecological transitions via the same physiological pathway. This finding provides a unifying mechanism to explain past results and underlines the profound threat anthropogenic stressors pose to fish communities.

References

Dec 1, 1989·General and Comparative Endocrinology·M Tagawa, T Hirano
Jul 4, 2002·The Journal of Biological Chemistry·Wayland LimJ David Furlow
Dec 13, 2005·Anatomy and Embryology·Ingibjörg Eir EinarsdóttirBjörn Thrandur Björnsson
Jul 15, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Helen M CraneJ Anne Brown
Jan 11, 2007·Proceedings of the National Academy of Sciences of the United States of America·Gabriele GerlachVanessa Miller-Sims
Mar 25, 2008·General and Comparative Endocrinology·Haruka Wada
Feb 5, 2009·Toxicological Sciences : an Official Journal of the Society of Toxicology·Simona De AngelisAlberto Mantovani
Apr 21, 2009·Environment International·Pamela D NoyesEdward D Levin
Jun 19, 2010·Science·Ove Hoegh-Guldberg, John F Bruno
Oct 1, 2011·Current Biology : CB·Vincent Laudet
Jul 25, 2012·Trends in Ecology & Evolution·Alexander D M Wilson, Jens Krause
Jan 26, 2013·Current Topics in Developmental Biology·Sarah K McMenamin, David M Parichy
May 21, 2013·Environmental Toxicology and Pharmacology·Theodore A SlotkinFrederic J Seidler
Feb 22, 2014·Current Biology : CB·Thomas W Holstein, Vincent Laudet
May 16, 2014·The Journal of Experimental Biology·Alexander G Little, Frank Seebacher
Feb 6, 2016·Nature Communications·Stephen D SimpsonMark G Meekan
Feb 13, 2016·Proceedings. Biological Sciences·Robin Hale, Stephen E Swearer
Jun 28, 2016·Environmental Science & Technology·Marie BigotSusan Bengtson Nash
Nov 1, 2016·Proceedings. Biological Sciences·Christopher Harry Robert Goatley, David Roy Bellwood
Dec 13, 2016·Science·Michael Tobler, Zachary W Culumber
Feb 25, 2017·Nature Communications·Atul BhardwajFrank Wuest
May 27, 2017·Molecular and Cellular Endocrinology·Jean-David GothiéSylvie Remaud
Oct 20, 2017·Nature Ecology & Evolution·Jacob L JohansenAndrew J Esbaugh
Jan 11, 2018·Nature Communications·Dakota E McCoyRichard O Prum
May 2, 2018·Proceedings of the National Academy of Sciences of the United States of America·Timothy A C GordonStephen D Simpson
Apr 3, 2019·International Journal of Molecular Sciences·Lisa BaumannLucia Vergauwen
Apr 26, 2019·Nature·Malin L PinskyJennifer M Sunday
Jun 23, 2019·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yinan HuSarah McMenamin
Nov 30, 2019·The Journal of Experimental Biology·Valerio TettamantiFabio Cortesi

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Citations

Jan 24, 2021·The Science of the Total Environment·Beatriz SuárezCarmen Freire
Nov 27, 2020·Frontiers in Endocrinology·Cole K Deal, Helene Volkoff
Feb 22, 2021·Environmental Pollution·Eli S J ThoréTom Pinceel
Jun 12, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Sascha C T NicklischAmro Hamdoun

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