PMID: 9533513Apr 9, 1998Paper

Anthropology of the apoplipoprotein E (apo E) gene: low frequency of apo E4 allele in Basques and in tribal (Baiga) populations of India

Annals of Human Biology
S S MastanaS S Papiha

Abstract

The distribution of apolipoprotein E (apo E) polymorphism was examined in 11 population groups not previously studied for this system. There is a marked difference in phenotype and gene frequency between the populations of England and Spain. The south European populations of Basques and Spanish non-Basques showed greater similarity to the populations of South Asia. The study clearly indicates that the distribution of apo E alleles does match with regions showing a high mortality rate of coronary heart disease. The data presented also indicate that authochthon groups such as Basques in Europe and tribals in India may throw better light on the role of apolipoproteins in the regulation of lipid levels in disease.

References

Jan 1, 1991·Human Heredity·J E EichnerM I Kamboh
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Citations

Nov 10, 2006·Annals of Human Biology·P P SinghS S Mastana
Jul 7, 2017·PloS One·Eric van ExelRudi G J Westendorp
Feb 27, 2008·Clinical Chemistry and Laboratory Medicine : CCLM·Ricardo GamboaGilberto Vargas-Alarcón
Jun 22, 2010·American Journal of Reproductive Immunology : AJRI·Meenal AgarwalSuraksha Agrawal
Mar 24, 2005·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Said Ali S Al-YahyaeeAli Hassan Al-Bahrani
Jun 27, 2020·Frontiers in Aging Neuroscience·Hussein N Yassine, Caleb E Finch
Dec 9, 2020·Ophthalmic Genetics·Marcelo Luís OcchiuttoVital Paulino Costa
Dec 22, 1999·Neurobiology of Aging·C E Finch, R M Sapolsky
Apr 20, 2006·Diabetes Research and Clinical Practice·Puneet Pal SinghSarabjit Mastana
Jan 10, 2012·Journal of Affective Disorders·R SureshkumarM Varghese

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