Anthropometric findings from birth to adulthood and their relation with karyotpye distribution in Turkish girls with Turner syndrome

American Journal of Medical Genetics. Part a
Erkan SariFeyza Darendeliler

Abstract

To evaluate the anthropometric features of girls with Turner syndrome (TS) at birth and presentation and the effect of karyotype on these parameters. Data were collected from 842 patients with TS from 35 different centers, who were followed-up between 1984 and 2014 and whose diagnosis age ranged from birth to 18 years. Of the 842 patients, 122 girls who received growth hormone, estrogen or oxandrolone were excluded, and 720 girls were included in the study. In this cohort, the frequency of small for gestational age (SGA) birth was 33%. The frequency of SGA birth was 4.2% (2/48) in preterm and 36% (174/483) in term neonates (P < 0.001). The mean birth length was 1.3 cm shorter and mean birth weight was 0.36 kg lower than that of the normal population. The mean age at diagnosis was 10.1 ± 4.4 years. Mean height, weight and body mass index standard deviation scores at presentation were -3.1 ± 1.7, -1.4 ± 1.5, and 0.4 ± 1.7, respectively. Patients with isochromosome Xq were significantly heavier than those with other karyotype groups (P = 0.007). Age at presentation was negatively correlated and mid-parental height was positively correlated with height at presentation. Mid-parental height and age at presentation were the only param...Continue Reading

References

Jan 1, 1979·Acta Paediatrica Scandinavica. Supplement·H L LenkoA Söderholm
Sep 15, 1991·American Journal of Medical Genetics·L PelzG Verron
Dec 1, 1991·Acta paediatrica Scandinavica·J KarlbergO Westphal
Jan 1, 1983·Pediatric Research·E ParkC A Cowell
Mar 1, 1994·Acta Paediatrica·P RochiccioliG Simonin
Apr 20, 2001·Journal of Pediatric Endocrinology & Metabolism : JPEM·R BundakO Neyzi
Jun 8, 2002·Hormone Research·Michael L DavenportVirginia P Sybert
May 24, 2003·BJOG : an International Journal of Obstetrics and Gynaecology·Jean-Marie Moutquin
Jun 8, 2006·The Journal of Clinical Endocrinology and Metabolism·Catherine E HamelinCheri L Deal
Jul 24, 2007·Journal of Pediatric Endocrinology & Metabolism : JPEM·Andrzej WisniewskiJolanta Szufladowicz-Wozniak
Mar 8, 2012·Journal of Clinical Research in Pediatric Endocrinology·Abdullah Bereket, Zeynep Atay
May 18, 2012·The Journal of Clinical Endocrinology and Metabolism·Marie DevernayJean-Claude Carel
Jun 6, 2012·Journal of Clinical Research in Pediatric Endocrinology·Selim KurtoğluOsman Baştuğ
Jul 1, 2010·Clinical Pediatric Endocrinology : Case Reports and Clinical Investigations : Official Journal of the Japanese Society for Pediatric Endocrinology·Tsuyoshi IsojimaToshiaki Tanaka
Mar 25, 2015·Journal of Clinical Research in Pediatric Endocrinology·Ediz YeşilkayaCarolyn Bondy

❮ Previous
Next ❯

Citations

Jun 14, 2019·Hormone Research in Pædiatrics·Jan M WitUNKNOWN on behalf of the Dutch Working Group on Triage and Diagnosis of Growth Disorders in Children

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
P R BlackettS L Blethen
Pediatrics International : Official Journal of the Japan Pediatric Society
Satomi InomataHidekuni Inadera
© 2022 Meta ULC. All rights reserved