Anti-counterfeiting protection, personalized medicines - Development of 2D identification methods using laser technology.

International Journal of Pharmaceutics
Krisztina LudasiGéza Regdon

Abstract

Counterfeiting of the products for healing is as old as trading, and it is difficult to quantify the magnitude of the problem. It is known that substandard and/or falsified (SF) medicines are a growing global threat to health, and they cause serious social and economic damage. The EU has a strong legal framework for medicines, it is mandatory to meet the requirements of Directive 2011/62/EU. Serialisation prevents SF medicinal products from entering the legal distribution chain. The present study is an extension of the original idea and aims to develop a laser technology-based method to mark an individual traceable code on the surface of the tablet, which technology can also be used for marking personalized medicines. The method is based on the ablation of the upper layer of a double-layer, differently coloured coating. The 2D code should be formed without harming the functional layer, and anyone with a smartphone integrated with a camera should be able to authenticate these drugs with a suitable application. The present findings confirmed that KrF excimer laser and Ti:sapphire femtosecond laser are efficient and reliable for marking. These should be promising candidates for pharmaceutical companies that would like to have addi...Continue Reading

References

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Jun 19, 2019·International Journal of Pharmaceutics·Sarah J TrenfieldAlvaro Goyanes
Nov 11, 2019·International Journal of Pharmaceutics·Matthias WolfgangJohannes G Khinast

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