Abstract
Epstein-Barr virus (EBV) is associated with nasopharyngeal carcinoma (NPC) which is prevalent in South China, and its association with systemic lupus erythematosus (SLE) or other autoimmune diseases has not been studied in the mainland of China. The EBV serological tests have been performed on patients with various diseases or manifestations for years at our institution and their values need to be evaluated. For routine medical purposes, anti-EB viral capsid antigen (VCA) IgG, IgA and IgM antibodies, anti-EBV diffuse early antigen (EA-D) IgA antibodies, and anti-EBV nuclear antigen-1(EBNA-1) IgG antibodies were tested with commercial enzyme-linked immunosorbent assay (ELISA) in patients visiting Peking Union Medical College Hospital between 2013 and 2017. The test results were analyzed in this retrospective study. There were a total of 11122 serum samples available to be tested in the study. As indicators of past EBV infection, the prevalence of VCA-IgG/EBNA1-IgG were 66.6%/58.5%, 84.3%/78.8%, 92.9%/87.0% and 98.5%/95.4% in patients aged under 5 years, 6-10 years, 11-20 years and 21-30 years old, respectively, and these values maintained at this highest rate as age increased further. The prevalence of VCA-IgM, as a parameter of...Continue Reading
References
Jan 1, 1991·Springer Seminars in Immunopathology·T OokaM C Stolzenberg
Aug 17, 2000·The New England Journal of Medicine·J I Cohen
Feb 25, 2006·Pathology International·Kengo TakeuchiShigeo Mori
Apr 17, 2007·Lupus·J J Y LuS H Lin
Aug 26, 2011·International Journal of Cancer. Journal International Du Cancer·Yue LiuMinghuang Hong
Jun 1, 2012·Scandinavian Journal of Rheumatology·A H DraborgK Duus
Jan 7, 2014·Arthritis Research & Therapy·Peter HanlonMark A Vickers
Apr 25, 2014·Journal of Medical Virology·Michele S BastosMaria Paula G Mourão
Jun 11, 2014·PloS One·Geng XiongYi-xin Zeng
Jul 6, 2014·PloS One·Weimin ZhouWenjie Tan
Sep 3, 2014·Diagnostic Microbiology and Infectious Disease·Michael KleinesMartin Häusler
Jan 7, 2015·Scandinavian Journal of Rheumatology·N S RasmussenG Houen
Jan 24, 2015·PloS One·Chao-Yu ChenYhu-Chering Huang
Mar 5, 2015·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Ching-Yi ChoKeh-Gong Wu
May 23, 2015·BioMed Research International·Marie Wulff WestergaardGunnar Houen
Aug 27, 2015·Infectious Diseases·Sofie Kathrine ToppMarie-Louise Von Linstow
Sep 25, 2015·PloS One·Anette H DraborgGunnar Houen
Mar 18, 2016·Current Opinion in Rheumatology·Anette DraborgGunnar Houen
Aug 25, 2016·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Seung Hyun OhSang Wook Choi
Nov 12, 2016·Central-European Journal of Immunology·Anna DittfeldRomuald Wojnicz
Apr 15, 2017·F1000Research·Brent A Stanfield, Micah A Luftig
Apr 18, 2017·PloS One·Grégoire FourcadeOlivier Epaulard
Apr 28, 2017·Scandinavian Journal of Gastroenterology·Hilmar LeonardssonEinar S Björnsson
Apr 30, 2017·Revista de salud pública·Vaneza TiqueLuiz T Moraes-Figueiredo
May 5, 2017·AIDS Research and Therapy·Rongrong YangDeyin Guo
Jul 25, 2017·Journal of Medical Virology·Durga ChouguleVandana Pradhan
Citations
Nov 22, 2019·Journal of Medical Virology·Jianrong ShiWei Li
Aug 29, 2019·PloS One·Jingtao CuiAnping Ni
Mar 10, 2020·Journal of Immunology Research·Yang ZhaoRong Fu
Aug 7, 2019·Immunology·Rebeca Illescas-MontesVíctor J Costela-Ruiz
Sep 24, 2019·Antibodies·Nicole Hartwig TrierGunnar Houen
Mar 7, 2021·Viruses·Marco QuagliaVincenzo Cantaluppi
Mar 16, 2021·British Journal of Biomedical Science·P NaughtonB Lucey
Mar 16, 2021·Journal of Medical Virology·Ting ShiJianmei Tian
Sep 18, 2021·Scientific Reports·Leonn Mendes Soares PereiraAntonio Carlos Rosário Vallinoto