Anti-hypertensive medications and injurious falls in an older population of low socioeconomic status: a nested case-control study

BMC Geriatrics
Zafirah BanuLian Leng Low

Abstract

This study aimed to determine whether the number of anti-hypertensive medication classes or any change in anti-hypertensive medication were associated with injurious fall among the community-dwelling older population of low socioeconomic status. Using data from electronic medical records, we performed a nested case-control study among older Singapore residents (≥60) of low socioeconomic status (N = 210). Controls (n = 162) were matched to each case (n = 48) by age and gender. Variables with p < 0.10 in univariate analysis were included in multivariate analysis. We used conditional logistic regression to assess the associations of the number of anti-hypertensive medication classes and change in anti-hypertensive medication with injurious falls. We also performed stepwise regressions as sensitivity analyses. p < 0.05 was considered statistically significant. The mean (±SD) age of participants was 78.1 (± 8.33) years; 127 (60.4%) were female, 189 (90.0%) were Chinese. Those on ≥2 anti-hypertensive medication classes had an increased risk of experiencing an injurious fall compared to those not on any anti-hypertensive medication (OR = 5.45; CI:1.49-19.93; p = 0.01). Among those who were taking anti-hypertensive medication, those wh...Continue Reading

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Citations

Mar 28, 2020·International Journal of Environmental Research and Public Health·Zhuang HongZhaorong Gao
Jun 18, 2021·BMC Geriatrics·Stijn CrutzenKatja Taxis
Apr 27, 2020·Journal of the American Medical Directors Association·Mehmet Ilkin Naharci, Ilker Tasci
Aug 28, 2021·International Journal of Environmental Research and Public Health·Atirah Az-Zahra Abu BakarSiti Nurbaya Mohd Nawi

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