Anti-inflammatory, analgesic, and antipyretic activities of virgin coconut oil

Pharmaceutical Biology
S IntahphuakA Panthong

Abstract

This study investigated some pharmacological properties of virgin coconut oil (VCO), the natural pure oil from coconut [Cocos nucifera Linn (Palmae)] milk, which was prepared without using chemical or high-heat treatment. The anti-inflammatory, analgesic, and antipyretic effects of VCO were assessed. In acute inflammatory models, VCO showed moderate anti-inflammatory effects on ethyl phenylpropiolate-induced ear edema in rats, and carrageenin- and arachidonic acid-induced paw edema. VCO exhibited an inhibitory effect on chronic inflammation by reducing the transudative weight, granuloma formation, and serum alkaline phosphatase activity. VCO also showed a moderate analgesic effect on the acetic acid-induced writhing response as well as an antipyretic effect in yeast-induced hyperthermia. The results obtained suggest anti-inflammatory, analgesic, and antipyretic properties of VCO.

References

May 1, 1989·Journal of General Internal Medicine·B V AkinH Waitzkin
Aug 1, 1987·Agents and Actions·M J DiMartinoN Hanna
Apr 1, 1971·The Journal of Pharmacy and Pharmacology·M Di Rosa, D A Willoughby
Jul 1, 1971·British Journal of Pharmacology·P Crunkhorn, S C Meacock
Jan 1, 1996·Clinical and Diagnostic Laboratory Immunology·K J WitcherP M Schlievert
Mar 24, 1998·General Pharmacology·M I SerranoM C Serrano-Martino
Oct 19, 2002·International Journal of Antimicrobial Agents·Gudmundur BergssonHalldor Thormar
Dec 1, 1962·Proceedings of the Society for Experimental Biology and Medicine·C A WINTERG W NUSS
May 1, 1963·Journal of Medicinal Chemistry·U M TEOTINOD DELLABELLA
Apr 1, 2004·Applied Biochemistry and Biotechnology·Carla C B PereiraMarta A P Langone

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Citations

Aug 29, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Mouna Abdelrahman AbujaziaIma Nirwana Soelaiman
Jan 1, 2014·International Journal of Food Science·Probir Kumar GhoshMousumi Poddar-Sarkar
Apr 4, 2015·Nigerian Medical Journal : Journal of the Nigeria Medical Association·Faizal C PeedikayilArun Narayanan
Jul 19, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Badlishah Sham Nurul-ImanHj Mohd Saad Qodriyah
Aug 11, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Allison L Goddard, Peter A Lio
May 11, 2015·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Shivaram Shivakumar BadamaranahalliSharanbasappa Durg
Feb 11, 2015·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Naiane F B AlvesValdir A Braga
Oct 27, 2015·European Journal of Nutrition·Hilary J BethancourtDaniel T A Eisenberg
Feb 13, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Mysrayn Y F A ReisKarina L A Saraiva
Sep 20, 2019·Journal of Complementary & Integrative Medicine·Lalgi HimaSrinivasan ThyagaRajan
Jun 13, 2020·Nutrition and Cancer·Arunaksharan NarayanankuttyAchuthan C Raghavamenon
Jul 1, 2017·International Journal of Inflammation·N A KamalaldinB Yahaya
Feb 25, 2020·Oxidative Medicine and Cellular Longevity·Luiz Henrique C VasconcelosBagnólia A da Silva
Oct 7, 2020·Journal of the Science of Food and Agriculture·Afka DeenRuvini Liyanage
Jan 19, 2020·Mechanisms of Ageing and Development·Pratishtha ChatterjeeRalph N Martins
Mar 31, 2021·International Journal of Pharmaceutics·Narimane LammariAbdelhamid Elaissari
Apr 13, 2021·Journal of Food Biochemistry·Zhao TianChi Shang
Apr 18, 2021·Journal of Food Science·Soorya Parathodi IllamAchuthan Chathrattil Raghavamenon
May 20, 2021·Bioprocess and Biosystems Engineering·Yan Jer NgPau Loke Show
Jun 1, 2021·Journal of Functional Foods·Imelda Angeles-AgdeppaKeith V Tanda
Jun 26, 2021·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Ifeanyichukwu ElekwaEziuche Amadike Ugbogu
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Irene Dini, Sonia Laneri
Aug 20, 2021·Drug and Chemical Toxicology·Soorya Parathodi IllamAchuthan C Raghavamenon

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