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Anti-phospho-tau Gene Therapy for Chronic Traumatic Encephalopathy

Human Gene Therapy

Oct 14, 2019

Chester Bittencourt SacramentoRonald G. Crystal

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Abstract

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder caused by repetitive trauma to the central nervous system (CNS) suffered by soldiers, contact sport athletes and civilians following accident-related trauma. CTE is a CNS tauopathy, with trauma-induced in...read more

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Dependovirus
Monoclonal Antibodies
Cerebral Cortex
Gene Therapy
Genetic Vectors
Hippocampus (Brain)
Inflammation
Laboratory mice
Mus
Neurons
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Anti-phospho-tau Gene Therapy for Chronic Traumatic Encephalopathy

Human Gene Therapy

Oct 14, 2019

Chester Bittencourt SacramentoRonald G. Crystal

PMID: 31608704

DOI: 10.1089/hum.2019.174

Abstract

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder caused by repetitive trauma to the central nervous system (CNS) suffered by soldiers, contact sport athletes and civilians following accident-related trauma. CTE is a CNS tauopathy, with trauma-induced in...read more

Mentioned in this Paper

Dependovirus
Monoclonal Antibodies
Cerebral Cortex
Gene Therapy
Genetic Vectors
1
1
2

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