PMID: 79760Aug 19, 1978Paper

Anti-prostglandin therapy in prevention of side-effects of intrauterine contraceptive devices

O YlikorkalaM Siljander


The efficacy of an anti-prostaglandin, tolfenamic acid (T.A.), in the prevention of side-effects after insertion of a copper-T200 intrauterine contraceptive device (I.U.D.) was evaluated in a double-blind trial in 160 women. T.A. relieved pain and reduced bleeding after insertion and during three subsequent menstruations without serious side-effects. A scoring system for the assessment of I.U.D. side-effects showed that the acceptability of I.U.D. was significantly better in women treated with T.A. than in those given placebo.


Mar 1, 1987·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·N D Goldstuck
Oct 1, 1979·Prostaglandins·A KauppilaO Ylikorkala
Oct 1, 1982·Prostaglandins, Leukotrienes, and Medicine·P V Peplow, P R Hurst
Mar 14, 1981·Lancet·G RyboK G Nygren
Nov 1, 1979·British Journal of Clinical Pharmacology·G J Sanger, A Bennett
Mar 1, 1995·British Journal of Pharmacology·T J Gelety, G Chaudhuri
Jan 1, 1994·Pharmacology & Toxicology·J DelgadoJ Yoma
Mar 22, 2014·The Journal of Family Planning and Reproductive Health Care·John Guillebaud
May 1, 1980·British Journal of Obstetrics and Gynaecology·G C ChristiaensA A Haspels
Dec 1, 1992·Baillière's Clinical Obstetrics and Gynaecology·I S Fraser
Jun 19, 2014·The Journal of Family Planning and Reproductive Health Care·Luis BahamondesKristina Gemzell-Danielsson
Oct 21, 2006·The Cochrane Database of Systematic Reviews·D A GrimesK F Schulz
Jan 1, 1980·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·A J Davies
Aug 3, 1985·British Medical Journal·A D Noble
Dec 1, 1981·Prostaglandins and Medicine·P V Peplow, P R Hurst
Jan 1, 1981·Prostaglandins and Medicine·P V Peplow, P R Hurst

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