Anti-Ro/SSA antibodies and cardiac rhythm disturbances: Present and future perspectives

International Journal of Cardiology
Irene Santos-PardoAntoni Bayes-Genis

Abstract

Several case reports, small case series, and original research papers have recently suggested that the action of certain auto-antibodies related to connective tissue diseases may be responsible for significant cardiac rhythm disturbances in adults. The relationship between anti-Ro/SSA antibodies and congenital complete atrioventricular block is well recognized in the fetal heart. Herein we review the emerging evidences of the link to increased levels of anti-Ro/SSA antibodies with rhythm disorders of unknown origin in the adult. Confirmation of this distinct etiology may eventually be the basis for new therapies.

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Citations

Jan 23, 2016·Frontiers in Cardiovascular Medicine·Pietro Enea LazzeriniFranco Laghi-Pasini
May 20, 2016·Rheumatology International·Ayse Nur TufanEdiz Dalkilic
Feb 27, 2020·Circulation Journal : Official Journal of the Japanese Circulation Society·Monika GawałkoJędrzej Kosiuk
Jan 15, 2021·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Mavi Maureen Rivera PavonPrecious Obehi Eseaton

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