Anti-thyroid peroxidase antibody and vitiligo: a controlled study

BMC Dermatology
Maryam DaneshpazhoohReza Mahmoud Robati

Abstract

Vitiligo is an acquired depigmenting disorder due to destruction of melanocytes. Although many theories have been suggested for its pathogenesis, the role of autoimmunity is the most popular one. The association of vitiligo with autoimmune thyroid diseases and the increased prevalence of autoantibodies including thyroid autoantibodies in vitiligo favor this role. Our objective was to compare the frequency of thyroid peroxidase antibody (anti-TPO) in vitiligo patients with healthy subjects in Iran. Ninety-four cases of vitiligo (46 female and 48 male) and 96 control subjects (49 female and 47 male) were enrolled in this controlled study. Patients with known thyroid disease, history of thyroid surgery and those receiving thyroid medications were not included. The two groups were matched regarding gender and age. The demographic data, symptoms related to thyroid diseases and results of skin and thyroid examinations were recorded in a questionnaire for each subject. Thyroid function tests including free T3, free T4 and TSH-IRMA were performed. Anti-TPO levels were assessed as well. The collected data were analyzed by SPSS version-11 in vitiligo patients and subgroups according to gender, age, extent, and duration of the disease com...Continue Reading

References

Apr 1, 1983·Archives of Dermatology·P E GrimesJ A Kenney
Jan 1, 1996·International Journal of Dermatology·R C MandryJ L Sánchez
May 8, 2003·Journal of the American Academy of Dermatology·Julia AiWarren R Heymann
May 20, 2003·Pigment Cell Research·Asem AlkhateebRichard A Spritz
Dec 18, 2003·Journal of the European Academy of Dermatology and Venereology : JEADV·A Kurtev, A L Dourmishev
Dec 18, 2004·Dermatology : International Journal for Clinical and Investigative Dermatology·Paolo IacovelliMauro Picardo

❮ Previous
Next ❯

Citations

May 24, 2013·Archives of Dermatological Research·Abdellatif BouayadM Essakalli
Jan 3, 2012·Indian Journal of Clinical Biochemistry : IJCB·Anju JainSurajeet Kumar Patra
Jan 1, 2008·Indian Journal of Dermatology·Moradi Sedighe, Ghafarpoor Gholamhossein
Jul 13, 2011·Journal of Thyroid Research·Emina Kasumagic-HalilovicNermina Ovcina-Kurtovic
Feb 6, 2016·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·James V HennesseyUNKNOWN American College of Endocrinology (ACE)
Sep 12, 2015·BioMed Research International·Gulcan Saylam KurtipekArzu Ataseven
Feb 6, 2015·Journal of Thyroid Research·R DashB S Manjunathswamy
Feb 13, 2014·The Journal of Dermatology·Qinghai ZengRong Xiao
Feb 3, 2015·Pediatric Dermatology·Mark Jean-Aan KohWei-Sheng Chong
Jun 19, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·M ArunachalamS Moretti
May 19, 2010·Journal of the European Academy of Dermatology and Venereology : JEADV·V IngordoL Naldi
Jul 2, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·S MorettiT Lotti
Dec 21, 2012·The British Journal of Dermatology·A GeyK Ezzedine
Jun 15, 2011·The Journal of Dermatology·Reza YaghoobiNooshin Bagherani
Jun 1, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·M KarelsonK Kingo
Nov 5, 2011·The British Journal of Dermatology·M W KroonJ P W van der Veen
May 15, 2010·International Journal of Dermatology·Taraneh Paravar, Delphine J Lee
Aug 7, 2012·The British Journal of Dermatology·C VrijmanP I Spuls
Feb 5, 2008·Clinical and Experimental Immunology·B FattoriF Monzani
Nov 4, 2016·Biochemical and Biophysical Research Communications·Rosa CarotenutoPaolo Russo
Jul 6, 2013·Arquivos brasileiros de endocrinologia e metabologia·Gabriela BrentaUNKNOWN Task Force on Hypothyroidism of the Latin American Thyroid Society (LATS)
Sep 1, 2015·Journal of Cutaneous Medicine and Surgery·Mohammad Javad YazdanpanahNaghmeh Zabolinejad
Jan 25, 2018·BioMed Research International·Vasanop VachiramonKumutnart Chanprapaph
Dec 16, 2018·Pigment Cell & Melanoma Research·Clément JacqueminUNKNOWN FHU ACRONIM
Jan 31, 2019·Frontiers in Endocrinology·Jinping YuanHong-Duo Chen
Jan 4, 2021·Molecular and Cellular Biochemistry·Navneet AroraSidharth Mehan
Aug 13, 2015·The Journal of Clinical Endocrinology and Metabolism·Jo Ana SchunterAntje Körner
Sep 16, 2021·Wiener medizinische Wochenschrift·Peter MikoschEva Trifina-Mikosch

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme linked immunosorbant assay

Software Mentioned

SPSS

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Autoimmune Thyroiditis

Autoimmune thyroiditis is an inflammatory disease of thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. Discover the latest research on autoimmune thyroiditis here.