Anti-Toxoplasma gondii immunoglobulins A and G in human saliva and serum

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
A M LoyolaJosé Roberto Mineo

Abstract

Paired human saliva and serum samples from 60 individuals were tested for specific IgA and IgG antibodies to Toxoplasma gondii. The study in both fluids was carried out by indirect immunoenzymatic assay (ELISA). Saline antigenic extract of T. gondii was used to coat plastic surfaces upon which the samples were then incubated; monospecific conjugates of anti-IgA and anti-IgG-peroxidase were then incubated with the samples after a washing procedure to separate the unbound antibodies. The enzymatic activity was measured and the results expressed in terms of ELISA index. Toxoplasma-specific IgG antibodies were detected in 43 of the serum samples (71.7%) and in 12 of the saliva samples (20.0%) whereas Toxoplasma-specific IgA antibodies were detected in 18 of the serum samples (30.0%) and in 12 of the saliva samples (20.0%). No association was observed when the Toxoplasma-specific IgG reactive and non-reactive serum samples were compared with the reactive and non-reactive saliva samples for this class of immunoglobulin. On the other hand, a significant association was observed when the Toxoplasma-specific IgA reactive and non-reactive serum samples were compared with the reactive and non-reactive saliva for this type of antibody. In ...Continue Reading

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Citations

Oct 9, 2004·Journal of Clinical Microbiology·Justus G GarwegMatthias Boehnke
Mar 14, 2014·Bioanalysis·Michael MacdonaldChamindie Punyadeera
Dec 15, 2015·Pediatrics and Neonatology·Sandra Pineda-MartínezMarcela Vela-Amieva
Oct 31, 2009·Memórias do Instituto Oswaldo Cruz·Maria Isabel LynchFernando Oréfice
Mar 25, 2018·Parasite Immunology·I Cañedo-SolaresD Correa
Feb 6, 2015·Clinical and Vaccine Immunology : CVI·Emmanuelle ChapeyFrançois Peyron
Sep 25, 2020·Parasite Immunology·Larissa Rodrigues BosquiIdessania Nazareth da Costa

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