Antiangiogenic therapy in the treatment of recurrent medulloblastoma in the adult: case report and review of the literature.

Journal of Oncology
Giuseppe PriviteraCorrado Spatola

Abstract

Medulloblastoma is a rare tumor in central nervous system, with an even rarer occurrence in adulthood. The management of a recurrent disease is a medical challenge; chemotherapy has been used as the treatment of choice, while reirradiation has been employed in selected cases. We report the case of a 51-year-old man with recurrent medulloblastoma. He was treated with local reirradiation, chemotherapy, and antiangiogenic drug, with the latter giving the longer progression-free interval. The aim of this report is to show that recurrent medulloblastoma in adults can be approached with a multimodality treatment and that antiangiogenic therapy should have a role in the management of this disease.

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Citations

Jan 9, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dolly AguileraRobert C Castellino
Nov 13, 2010·Pediatric Blood & Cancer·Dolly G AguileraJason Fangusaro
Jan 21, 2015·Critical Reviews in Oncology/hematology·Alba A BrandesEnrico Franceschi
Jul 24, 2013·Journal of Neuro-oncology·Xanthoula Kostaras, Jacob C Easaw
Jun 27, 2019·Current Treatment Options in Oncology·Nazanin Majd, Marta Penas-Prado
Dec 6, 2018·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Aleksandra NapieralskaSławomir Blamek
Apr 1, 2014·Journal of Investigative Medicine High Impact Case Reports·Abhimanyu GhoseSadia Benzaquen

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Methods Mentioned

BETA
surgical resection

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