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Antiarrhythmic and hemodynamic effects of an aminosteroid (Org 3001) in the digitalized dog

European Journal of Pharmacology

Mar 1, 1976

W J RemmeF Hagemeyer

Abstract

Org 6001 (3alpha-amino-5alpha-androstan-2beta-ol-17-one-hydrochloride) is an orally non-hormonal aminosteroid possessing antiarrhythmic activity. In 13 dogs the efficacy of the drug against ouabain-induced ventricular tachycardia (VT) was studied. VT was produced by a mean dose of 67.5 ...read more

Mentioned in this Paper

Left Ventricular Structure
Pulse Rate
Androstanes
Sketetal Dysplasia Coarse Facies Mental Retardation
Cardiac Depressants
Ouabain
Aortic Diseases
Cardiac Arrhythmia
Tachycardia
Metazoa
Paper Details
References

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Antiarrhythmic and hemodynamic effects of an aminosteroid (Org 3001) in the digitalized dog

European Journal of Pharmacology

Mar 1, 1976

W J RemmeF Hagemeyer

PMID: 1261591

DOI: 10.1016/0014-2999(76)90271-5

Abstract

Org 6001 (3alpha-amino-5alpha-androstan-2beta-ol-17-one-hydrochloride) is an orally non-hormonal aminosteroid possessing antiarrhythmic activity. In 13 dogs the efficacy of the drug against ouabain-induced ventricular tachycardia (VT) was studied. VT was produced by a mean dose of 67.5 ...read more

Mentioned in this Paper

Left Ventricular Structure
Pulse Rate
Androstanes
Sketetal Dysplasia Coarse Facies Mental Retardation
Cardiac Depressants
Ouabain
Aortic Diseases
Cardiac Arrhythmia
Tachycardia
Metazoa

Related Papers

Paper Details
References
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