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Antiarrhythmic and hemodynamic effects of an aminosteroid (Org 3001) in the digitalized dog

European Journal of Pharmacology

Mar 1, 1976

Willem J RemmeF Hagemeyer

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Abstract

Org 6001 (3alpha-amino-5alpha-androstan-2beta-ol-17-one-hydrochloride) is an orally non-hormonal aminosteroid possessing antiarrhythmic activity. In 13 dogs the efficacy of the drug against ouabain-induced ventricular tachycardia (VT) was studied. VT was produced by a mean dose of 67.5 ...read more

Mentioned in this Paper

Tachycardia, Ventricular
Cardiac Output
Canis familiaris
Aortic Diseases
Metazoa
17-Ketosteroids
Cardiac Depressants
Depression, Chemical
Sketetal Dysplasia Coarse Facies Mental Retardation
Androstanes
Paper Details
References
  • References10
  • Citations2
1

Antiarrhythmic and hemodynamic effects of an aminosteroid (Org 3001) in the digitalized dog

European Journal of Pharmacology

Mar 1, 1976

Willem J RemmeF Hagemeyer

PMID: 1261591

DOI: 10.1016/0014-2999(76)90271-5

Abstract

Org 6001 (3alpha-amino-5alpha-androstan-2beta-ol-17-one-hydrochloride) is an orally non-hormonal aminosteroid possessing antiarrhythmic activity. In 13 dogs the efficacy of the drug against ouabain-induced ventricular tachycardia (VT) was studied. VT was produced by a mean dose of 67.5 ...read more

Mentioned in this Paper

Tachycardia, Ventricular
Cardiac Output
Canis familiaris
Aortic Diseases
Metazoa

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Paper Details
References
  • References10
  • Citations2
1

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