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Antiarrhythmic, haemodynamic and metabolic effects of 3alpha-amino-5alpha-androstan-2beta-ol-17-one hydrochloride in greyhounds following acute coronary artery ligation

British Journal of Pharmacology

Nov 1, 1975

R J Marshall, J R Parratt

PMID: 1133

Abstract

1 The antiarrhythmic, haemodynamic and metabolic effects of a new amino steroid, ORG6001, have been investigated in experimental acute myocardial infarction in anaesthetized greyhounds. 2 ORG6001 administered either intravenously (2-10 mg/kg) or orally (50 mg/kg) significantly reduced t...read more

Mentioned in this Paper

Diastolic Blood Pressure
Myocardium
Myocardial Infarction
Cardiomyopathies
Androstanes
Cardiac Depressants
Sinus Node Artery
Heart
17-Ketosteroids
Hemodynamics
Paper Details
References
  • References17
  • Citations15
12
  • References17
  • Citations15
12

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Antiarrhythmic, haemodynamic and metabolic effects of 3alpha-amino-5alpha-androstan-2beta-ol-17-one hydrochloride in greyhounds following acute coronary artery ligation

British Journal of Pharmacology

Nov 1, 1975

R J Marshall, J R Parratt

PMID: 1133

DOI:

Abstract

1 The antiarrhythmic, haemodynamic and metabolic effects of a new amino steroid, ORG6001, have been investigated in experimental acute myocardial infarction in anaesthetized greyhounds. 2 ORG6001 administered either intravenously (2-10 mg/kg) or orally (50 mg/kg) significantly reduced t...read more

Mentioned in this Paper

Diastolic Blood Pressure
Myocardium
Myocardial Infarction
Cardiomyopathies
Androstanes
Cardiac Depressants
Sinus Node Artery
Heart
17-Ketosteroids
Hemodynamics

Similar Papers Found In These Feeds

Heart Rhythm & Arrythmias

Heart arrhythmias, also known as irregular heartbeat or cardiac dysrhythmia, are a group of conditions where the heartbeat is irregular (dysrhythmia), too slow (bradycardia), or too fast (tachycardia). Discover the latest research on heart rhythm and arrythmias here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

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Paper Details
References
  • References17
  • Citations15
12
  • References17
  • Citations15
12
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