Antibacterial activity of fluoroquinolones in combination with zidovudine

Journal of Medical Microbiology
C S LewinS G Amyes

Abstract

Since patients with AIDS may receive fluoroquinolones concurrently with zidovudine, the antibacterial interaction of these drugs was investigated. No evidence was found of antagonism between zidovudine and ciprofloxacin, DR-3355, enoxacin, lomefloxacin or ofloxacin against enterobacteria, staphylococci or Pseudomonas aeruginosa. Furthermore, the bactericidal activity of the fluoroquinolones against selected enterobacteria in nutrient broth was not affected by a clinically achievable concentration of zidovudine. It seems unlikely that zidovudine will have an adverse effect on the antibacterial activity of the fluoroquinolones in patients with AIDS.

Citations

Apr 16, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A Doléans-JordheimL P Jordheim
Jun 1, 1993·FEMS Immunology and Medical Microbiology·M T MascellinoS Farinelli
Dec 15, 2005·Southern Medical Journal·J Michael Kilby
May 18, 2012·TheScientificWorldJournal·Mohammed DwidarByoung-In Sang
Jun 28, 2019·Frontiers in Cellular and Infection Microbiology·Lucie PeyclitJean-Marc Rolain

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
H C Neu
Annual Review of Medicine
H C Neu
Reviews of Infectious Diseases
S J Sperber, C J Schleupner
© 2021 Meta ULC. All rights reserved