Antibacterial and antioxidant activities of quercetin oxidation products from yellow onion (Allium cepa) skin

Journal of Agricultural and Food Chemistry
Freddy A RamosMinoru Takeuchi

Abstract

Four new quercetin-derived oxidation products (1-4) and lunularin-4-O-beta-D-glucoside (5) were isolated from a water extract of onion (Allium cepa) skin, together with 17 other known compounds. Antibacterial assays for the isolated compounds showed that 2-(3,4-dihydroxyphenyl)-4,6-dihydroxy-2-methoxybenzofuran-3-one (1) presented selective activity against Helicobacter pylori strains and 3-(quercetin-8-yl)-2,3-epoxyflavanone (4) showed antibacterial activity against MRSA and H. pylori strains at the same time that it increased susceptibility of MRSA to beta-lactams. Evaluation of antioxidant activity against DPPH for the isolated compounds showed that the new derivative compounds (1-4) and 2,5,7,3',4'-pentahydroxy-3,4-flavandione (6) are more active than quercetin.

References

Nov 1, 1971·Canadian Journal of Microbiology·J J ChildH G Krishnamurty
Jun 22, 2000·Archives of Biochemistry and Biophysics·H M AwadI M Rietjens
Nov 1, 2002·Phytotherapy Research : PTR·Gareth GriffithsBrian Smith
Jan 28, 2005·Antimicrobial Agents and Chemotherapy·Hirofumi ShibataTomihiko Higuti

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Citations

Aug 2, 2013·Journal of Food Science and Technology·Zied Khiari, Dimitris P Makris
Feb 4, 2012·Journal of Agricultural and Food Chemistry·Agnès MilletIrmgard Merfort
Aug 15, 2012·Journal of Agricultural and Food Chemistry·Kevin HuvaereLeif H Skibsted
Jan 1, 2013·International Journal of Medicinal Chemistry·Balwinder SinghMohan Paul Singh Ishar
Apr 20, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zhonglei WangXiaohua Zhang
Nov 18, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Supatcharee SiriwongGriangsak Eumkeb
Aug 19, 2015·The Journal of Nutritional Biochemistry·Min-Jung SeoBoo-Yong Lee
Mar 31, 2016·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Anke Hartmann
Jan 16, 2013·Critical Reviews in Microbiology·Praveen RishiIndu Pal Kaur
May 21, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Jiyoung MoonMin-Jeong Shin
Aug 6, 2016·BMC Pharmacology & Toxicology·Supatcharee SiriwongGriangsak Eumkeb
Feb 7, 2017·Journal of Natural Products·Chung Sub KimKang Ro Lee
Sep 25, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Qiao-Mei RuYu-Ting Ding
Jul 25, 2018·Critical Reviews in Food Science and Nutrition·Joaheer D TeshikaMahomoodally M Fawzi
Oct 4, 2006·Rapid Communications in Mass Spectrometry : RCM·Nadja BuchnerLothar W Kroh
Oct 11, 2019·The New Phytologist·Pradeep Kumar SudheeranNoam Alkan
Oct 19, 2019·Natural Product Reports·Jonas KühlbornTill Opatz
Mar 11, 2017·Natural Product Research·Lynda GoleaHamada Haba
Mar 17, 2020·Cell & Bioscience·Asma VafadarHamed Mirzaei
Mar 24, 2018·Journal of Food and Drug Analysis·Kavita SharmaYong Rok Lee
Feb 14, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lucia PucciariniRoccaldo Sardella
Sep 27, 2018·BMC Pharmacology & Toxicology·Rezvan Enteshari NajafabadiSaeed Nazifi
Dec 13, 2019·Frontiers in Chemistry·Alejandro Vásquez-EspinalWilliam Tiznado
Jan 17, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Cinzia PaganoLuana Perioli

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