Antibacterial, anticancer and antioxidant potential of silver nanoparticles engineered using Trigonella foenum-graecum seed extract

IET Nanobiotechnology
Shivangi GoyalSurendra Nimesh

Abstract

In this study, the authors report a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using Trigonella foenum-graecum (TFG) seed extract. They explored several parameters dictating the biosynthesis of TFG-AgNPs such as reaction time, temperature, concentration of AgNO3, and TFG extract amount. Physicochemical characterisation of TFG-AgNPs was done on dynamic light scattering (DLS), field emission electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy. The size determination studies using DLS revealed of TFG-AgNPs size between 95 and 110 nm. The antibacterial activity was studied against Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Staphylococcus aureus. The biosynthesised TFG-AgNPs showed remarkable anticancer efficacy against skin cancer cell line, A431 and also exhibited significant antioxidant efficacy.

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Citations

Jul 25, 2019·Current Pharmaceutical Design·Xavier-Ravi BaskaranWenbo Liao
Jan 1, 2019·Medical Mycology·Júlia de Souza Silveira ValenteDaniela Isabel Brayer Pereira
Feb 2, 2019·Current Medicinal Chemistry·Mário FernandesAndreia C Gomes
Feb 17, 2021·Applied Microbiology and Biotechnology·Bilal JavedNaveed Iqbal Raja

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