Abstract
Four new 9',10'-dihydro-biphenanthrenes, including an unprecedented 1,2'-linked biphenanthrene, 4,7,3',5'-tetramethoxy-9',10'-dihydro(1,2'-biphenanthrene)-2,7'-diol (1), a new 1,3'-linked biphenanthrene, 4,7,7'-trimethoxy-9',10'-dihydro(1,3'-biphenanthrene)-2,2',5'-triol (2), and two new 1,1'-linked biphenanthrenes, 4,7,4'-trimethoxy-9',10'-dihydro(1,1'-biphenanthrene)-2,2',7'-triol (3) and 4,7,3',5'-tetramethoxy-9',10'-dihydro(1,1'-biphenanthrene)-2,2',7'-triol (4), as well as two known biphenanthrenes (5, 6), were isolated from a 95% ethanol extract of the fibrous roots of Bletilla striata. Their structures were determined by spectroscopic and spectrometric methods. Atropisomerism of these compounds was considered based on their chiral optical properties and potential energy surface scans at the ab initio HF/3-21G level, which revealed their racemic mixture form. Compounds 2-6 showed potent antibacterial activities against six Gram-positive bacterial strains.
References
Oct 26, 2002·Chemical Communications : Chem Comm·Tetsutaro HattoriSotaro Miyano
Mar 15, 2003·The Journal of Organic Chemistry·Tetsutaro HattoriSotaro Miyano
Jun 24, 2006·Journal of Natural Products·Zhen XueLan He
Feb 5, 2008·Phytochemistry·Adriána KovácsJudit Hohmann
Jul 6, 2010·Fitoterapia·Minghui YangZhongtao Ding
Mar 2, 2011·ChemMedChem·Steven R LaPlanteOliver Hucke
Mar 8, 2011·Microbial Biotechnology·Xue-Chang WuHaichun Gao
Citations
Jun 1, 2016·Journal of Asian Natural Products Research·S XiaoDe-Lin Xu
Jun 17, 2016·Journal of Natural Products·Xue-Ming ZhouChong-Ge Sun
Oct 27, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Florence AuberonAnnelise Lobstein
Dec 3, 2016·Fitoterapia·Florence AuberonAnnelise Lobstein
Jun 16, 2017·Journal of Asian Natural Products Research·Yang ZhaoChu-Tse Wu
Dec 27, 2018·Journal of Asian Natural Products Research·Yun-Yao KangYan-Fang Li
Sep 11, 2019·International Journal of Molecular Sciences·Fusheng JiangGuiyuan Lv
Jun 27, 2020·Functional Plant Biology : FPB·Bao-Wei LuJun Liu
Dec 3, 2016·BMC Complementary and Alternative Medicine·Jing-Jing GuoChao-Dong Qian
Aug 2, 2018·Frontiers in Microbiology·Bo-Chen ChenChao-Dong Qian
Feb 13, 2019·Translational Neuroscience·Guoqing ZhaoLongyun Li
Aug 23, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Liang LiuPeng-Fei Tu
Aug 10, 2016·Chemistry & Biodiversity·Joon Young BaeBang Yeon Hwang
May 24, 2017·BMC Complementary and Alternative Medicine·Ya ShiDongqing Cheng
Dec 18, 2019·BMC Complementary and Alternative Medicine·Yu-Yao ZuZhi-Shan Ding
Nov 19, 2019·Frontiers in Pharmacology·Delin XuJishuang Chen
Jan 28, 2021·Journal of Fungi·Xinhua ZengWeichang Huang
Dec 31, 2020·Plants·Xinhua ZengWeichang Huang
Mar 7, 2021·Plants·May Thazin ThantKittisak Likhitwitayawuid
Mar 30, 2021·Frontiers in Pharmacology·Richa Kusuma WatiBarbara Gravendeel
Mar 28, 2021·Food Chemistry·Alexsandra Iarlen Cabral CruzNorma Suely Evangelista-Barreto
May 1, 2021·Indian Journal of Microbiology·Xue-Jiao HuangChao-Dong Qian
May 2, 2021·Journal of Ethnopharmacology·Xingyu ZhangMeifeng Liu
May 14, 2021·Fitoterapia·Jian SuiYang Ye
Jun 19, 2021·Journal of Ethnopharmacology·Sai JiangWei Wang
Dec 28, 2017·Journal of Natural Products·Barbara TóthAndrea Vasas