Antibacterial efficacy of leaf extracts of Combretum album Pers. against some pathogenic bacteria

BMC Complementary and Alternative Medicine
Sunanda BurmanGoutam Chandra

Abstract

Plant derived medicines show significant contributions to mankind in treating infections of pathogenic bacteria. Recently plants are used in pharmaceutical industries for novel drug preparations because to ensure efficacy and safety as synthetic antibiotics are threatened for their multidrug resistance. The present study aimed at finding antibacterial potential of aqueous and ethanolic leaf extracts of Combretum album. Antibacterial activity was evaluated against seven bacterial strains by determining minimum inhibitory concentration (MIC) and zone of inhibition. Diameters of the zone of inhibition were compared with standard antibiotics. Preliminary phytochemical screening was done according to standard protocol. FTIR analysis was performed to identify the general phytochemical groups of compounds in the extract. All experiments were conducted in triplicate and values were expressed as the mean ± standard deviation. One-way analysis of variance (ANOVA) and Tukey tests were performed for statistical justification. Maximum zones of inhibition were found in case of ethanolic extracts in the following order Bacillus licheniformis (MTCC 530) > Pseudomonas aeruginosa (MTCC 2453) > Bacillus subtilis (MTCC 441) >, Pseudomonas fluoresc...Continue Reading

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Citations

Jan 24, 2020·Journal of Evidence-based Integrative Medicine·Maximilienne Ascension NyegueFrançois-Xavier Etoa
Mar 3, 2020·Expert Opinion on Drug Delivery·Yijie SongNing Zhang
Nov 9, 2019·Current Drug Discovery Technologies·Goutam ChandraIndranil Bhattacharjee
Jan 27, 2021·Journal of Toxicology and Environmental Health. Part a·Herbert Gonzaga SousaElcilene Alves de Sousa
Mar 9, 2019·Journal of Ayurveda and Integrative Medicine·Rajesh Kumar SinghSantosh Kumar Singh

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Methods Mentioned

BETA
infrared spectroscopy

Software Mentioned

MS Excel
Stat plus

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