Antibacterial properties of 5-substituted derivatives of rhodanine-3-carboxyalkyl acids

Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents
Waldemar TejchmanPiotr Suder

Abstract

A series of rhodanine 3-carboxyalkanoic acid derivatives possessing 4'-(N,N-dialkyl-amino or diphenylamino)-benzylidene moiety as a substituent at the C-5 position were synthesised and their antibacterial activity was screened. All the rhodanine derivatives showed bacteriostatic or bactericidal activity to the reference gram-positive bacterial strains, but lack of activity to the reference Gram-negative bacterial strains and yeast strains was observed.

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Citations

Oct 12, 2017·Expert Opinion on Drug Discovery·Danylo KaminskyyRoman Lesyk
Apr 4, 2019·Artificial Cells, Nanomedicine, and Biotechnology·Seyyed Mojtaba MousaviAli Mohammad Amani
Nov 30, 2019·Expert Opinion on Drug Discovery·Suresh MaddilaSreekantha B Jonnalagadda
Feb 7, 2020·Pharmaceuticals·Micheline DrayeRomain Duwald
Oct 30, 2019·Mini Reviews in Medicinal Chemistry·Navjot Singh SethiRajesh K Singh
Aug 26, 2019·Journal of Molecular Modeling·Katarzyna KobyłkaKrzysztof K Zborowski
Apr 29, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Volodymyr HorishnyMarina Sokovic
May 1, 2020·International Journal of Biological Macromolecules·T A ZidanE G Zaki

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Methods Mentioned

BETA
NMR

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