Abstract
Self-reported antibiotic allergies are common among hospitalized adults and children. However, there is a paucity of studies investigating the impact of an antibiotic allergy label in childhood. To investigate the impact of antibiotic allergy labeling on clinical outcomes in children. A retrospective study was conducted in a major pediatric tertiary hospital to capture inpatient admissions (N = 1672) in April 2014 and April 2015. Data, collected by chart review, included documented antibiotic allergy labels, antibiotic prescriptions, admitting specialty, hospital length of stay, and hospital readmissions. Of the 1672 pediatric patients surveyed, 58.1% were male and 44.8% were prescribed antibiotics. Antibiotic allergy labels were recorded in 5.3% of patients; most were β-lactam allergy labels (85%), mostly to unspecified penicillins. There was an increasing incidence of antibiotic allergy label with age, which was statistically significant (P < .001); no sex effect was seen. Patients with antibiotic allergy labels received more macrolide (P = .045), quinolones (P = .01), lincosamide (P < .001), and metronidazole (P = .009) antibiotics than did patients without an antibiotic allergy label. After adjusting for patient age, sex, p...Continue Reading
Citations
May 3, 2019·Allergy·Cosby A StoneElizabeth J Phillips
Aug 6, 2019·Paediatric Anaesthesia·Bojana StepanovicBritta S von Ungern-Sternberg
Feb 29, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Bernardo Sousa-PintoJoão Almeida Fonseca
Sep 18, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Trahern W JonesAdam L Hersh
Feb 27, 2020·Asia Pacific Allergy·Bernard Yu-Hor ThongRuby Pawankar
Sep 10, 2020·Frontiers in Pharmacology·Mara Morelo Rocha Felix, Fábio Chigres Kuschnir
Nov 13, 2020·British Journal of Clinical Pharmacology·Haifa Ben RomdhaneKarim Aouam
May 29, 2020·Allergologia et immunopathologia·E Dias de CastroJ R Cernadas
Dec 15, 2020·Revista brasileira de anestesiologia·Dirceu SoléFlavio Sano
Jan 13, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Anne L Fuhlbrigge, Sunita Sharma
Jun 28, 2019·The Journal of Allergy and Clinical Immunology·Rachel L MillerAleena Banerji
Mar 17, 2021·Journal of Paediatrics and Child Health·Margaret TaylorDebra Palazzi
Jul 7, 2019·The Journal of Allergy and Clinical Immunology. in Practice·David LutzS Shahzad Mustafa
Oct 17, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Nathan M KrahAdam L Hersh
Jul 30, 2021·Journal of Paediatrics and Child Health·Kobi J RischinBrendan McMullan
Aug 6, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Helen WangCathleen Collins
Aug 14, 2021·British Journal of Clinical Pharmacology·Anthony C CatalanoAmanda Gwee
Jan 16, 2022·Clinical Reviews in Allergy & Immunology·Karen M AnsteyIris M Otani