PMID: 11333588May 3, 2001Paper

Antibiotic prophylaxis and hernia repair. Systematic quantitative review results

Enfermedades infecciosas y microbiología clínica
F Javier Sánchez-ManuelJ Lozano-García

Abstract

The usefulness of the antibiotic prophylaxis in hernia repair is currently a controversial subject. Comparative studies have shown disparate results, and that is why it is difficult to have a clear idea of its utility. The purpose of the present study is to make a systematic quantitative review or meta-analysis of the published controlled studies on antibiotic prophylaxis in hernia repair, to give the best possible evidence as to the effectiveness of this prophylaxis. The described steps for the realization of a systematic quantitative review, based on the practice of evidence based medicine, have been followed. The steps are these: formulation of a relevant question (is antibiotic prophylaxis useful in open inguinal hernia repair in the prevention of post-operative infection of surgical wound?), search of the best available evidence, selection criteria of those trials found, analysis of each one of them, combination of the results (Yusuf and Peto method) and conclusions.Results. Twelve studies were found, of which eight fulfilled the inclusion criteria for the meta-analysis. Our results show that antibiotic prophylaxis in hernia repair, whether prosthetic material is used or not, diminishes the rate of infection by 42%, 61% an...Continue Reading

Citations

Dec 8, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Osvaldo Iribarren, Miguel Araujo

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