Abstract
Bacterial infections occurring during labour, childbirth, and the puerperium may be associated with considerable maternal and perinatal morbidity and mortality. Antibiotic prophylaxis might reduce wound infection incidence after an episiotomy, particularly in situations associated with a higher risk of postpartum perineal infection, such as midline episiotomy, extension of the incision, or in settings where the baseline risk of infection after vaginal birth is high. However, available evidence is unclear concerning the role of prophylactic antibiotics in preventing infections after an episiotomy. To assess whether routine antibiotic prophylaxis before or immediately after incision or repair of episiotomy for women with an uncomplicated vaginal birth, compared with either placebo or no antibiotic prophylaxis, prevents maternal infectious morbidities and improves outcomes. We searched the Cochrane Pregnancy and Childbirth's Trials Register, LILACS, ClinicalTrials.gov, and the WHO International Clinical Trials Registry Platform (ICTRP) on 24 July 2017, and screened reference lists of retrieved studies. We considered randomised controlled trials, quasi-randomised trials, and cluster-randomised trials that compared the use of routin...Continue Reading
References
May 5, 2005·JAMA : the Journal of the American Medical Association·Katherine HartmannKathleen N Lohr
Sep 1, 2005·Birth·Ian D GrahamJennifer Mary Medves
Sep 20, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·N KroppF Althabe
May 6, 2008·Journal of Midwifery & Women's Health·Nell Tharpe
Jan 23, 2009·The Cochrane Database of Systematic Reviews·Guillermo Carroli, Luciano Mignini
Apr 9, 2010·Current Opinion in Infectious Diseases·Jeroen van DillenJos van Roosmalen
Jun 18, 2010·The Cochrane Database of Systematic Reviews·Christine KettleKhaled Mk Ismail
Nov 6, 2010·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Julie van SchalkwykUNKNOWN Society of Obstetricians and Gynaecologists of Canada Infectious Diseases Committee
May 25, 2011·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists
Oct 12, 2012·PLoS Medicine·Courtney A GravettMatthew S Steele
Nov 16, 2012·The Cochrane Database of Systematic Reviews·Christine KettleKhaled Mk Ismail
Feb 4, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A Kamel, M Khaled
Aug 12, 2014·The Lancet Global Health·Lale SayLeontine Alkema
Oct 8, 2014·The Cochrane Database of Systematic Reviews·Pranom BuppasiriBandit Thinkhamrop
Oct 14, 2014·The Cochrane Database of Systematic Reviews·Tippawan LiabsuetrakulQ Monir Islam
Jan 15, 2015·JAMA : the Journal of the American Medical Association·Alexander M FriedmanJason D Wright