Abstract
Antibiotic prophylaxis is an effective tool to reduce surgical infection rates. However, antibiotic prophylaxis in cholecystectomy is controversial when non-high risk patients are considered. This research aims to evaluate the adherence with antibiotic prophylaxis protocol in patients undergoing cholecystectomy, and its impact in the outcomes of surgical infection. This single-center observational and retrospective study analyzed all elective cholecystectomy procedures carried out at the Fundación Alcorcón University Hospital in the period 2007-2014. Data were recovered from hospital records; rates of adherence to the available hospital protocols were evaluated for choice, initiation, duration, administration route and dosages of antibiotics, and the starting and duration of the prophylaxis. The overall adequacy rate to protocol was 72%. The adherence rates in both the administration route and dose were 100%. The most common violations of the protocol included the choice of antibiotic agent (19%), followed by the moment of initiating its administration (8.9%). The overall wound infection rate was lower in case of laparoscopy than in laparotomy cholecystectomy (1.4% vs. 4.3%, p < 0.05; odds rate [OR] 0.29, 95% confidence interva...Continue Reading
References
Jan 15, 2000·Archives of Surgery·A TocchiF Maggiolini
Jun 13, 2003·Surgical Endoscopy·M KocN Ozalp
Apr 12, 2005·American Journal of Surgery·Dale W BratzlerUNKNOWN Surgical Infection Prevention Guideline Writers Workgroup
May 25, 2006·American Journal of Surgery·Wen-Tsan ChangPai-Ching Sheen
Dec 29, 2006·Cirugía española·R Villeta PlazaPedro Ruiz López
Mar 8, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marjo E E van KasterenInge C Gyssens
Jun 10, 2008·American Journal of Infection Control·Teresa C HoranMargaret A Dudeck
Sep 10, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Abhishek ChoudharyPraveen K Roy
Dec 23, 2008·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Gilberto Guzmán-Valdivia
Dec 25, 2008·Journal de chirurgie·S MalavaudB Suc
Apr 29, 2009·American Journal of Infection Control·Gregory de LissovoyBrian B Vaughn
Jul 31, 2010·Journal of the American College of Surgeons·Angela M IngrahamBruce Lee Hall
Dec 15, 2010·The Cochrane Database of Systematic Reviews·Alvaro SanabriaGabriel Gomez
Feb 22, 2011·Enfermedades infecciosas y microbiología clínica·Cristina Díaz-Agero-PérezUNKNOWN Grupo de Trabajo INCLIMECC de la Comunidad de Madrid
Sep 21, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Yi MuScott K Fridkin
Jan 30, 2013·Enfermedades infecciosas y microbiología clínica·Miquel Pujol, Enric Limón
Apr 18, 2013·Surgical Infections·Branko BogdanicMaja Vanek
Aug 24, 2013·JAMA Surgery·John ShepardTrish Perl
Dec 18, 2013·The British Journal of Surgery·G JaafarG Sandblom
Sep 6, 2014·PloS One·Yoichi MatsuiA-Hon Kwon