PMID: 7036089Jan 9, 1982

Antibiotic prophylaxis in surgery (author's transl)

La Nouvelle presse médicale
S Kernbaum

Abstract

Post-operative infections are of course due to bacterial contamination, but also to local conditions favourable to bacterial growth, and to lowering of host defences. Antibiotic prophylaxis is indicated in "clean-contamined" surgery, in surgery on immunodepressed patient and in bone prosthesis. The risk is mainly ecological. Antibiotics are useless when administered after the first post-operative day. The results of well-conducted controlled studies demonstrating, for instance, the value of metronidazole in surgery of the large bowel and appendix are reported.

Related Concepts

Antibiotics
Clinical Trials
Bayer 5360
Premedication
Preoperative Procedure

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