Antibiotic prophylaxis prior to urodynamic study in patients with traumatic spinal cord injury. Is there an indication?

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Marcello Torres da SilvaP S S Beraldo

Abstract

Retrospective cohort of patients with traumatic spinal cord injury (SCI) that have been hospitalized for physical-functional rehabilitation purposes. To compare the incidence of urinary tract infection (UTI) after urodynamic study (UDS) in three hospitals that adopted different protocols with regard to the preparation of patients. Sarah Network of Rehabilitation Hospitals, Brazil. Between 2014 and 2015, 661 patients from three units of the same hospital network, one of which does not use antimicrobial prophylaxis independently of urine culture results, were evaluated after having undergone UDS. The results were compared in both univariate and multivariate analyses (logistic regression). The global rate of UTI after UDS was that of 3.18% (IC 95% 2.1-4.8), with no differences between the units. In the univariate analysis the only variable that was associated with UTI after UDS was that of T6 injuries or above (P = 0.029). The logistic regression has confi rmed this result, with an adjusted odds ratio of 3.06 (IC 95% 1.01 to 9.26; P = 0.0476). The use of antimicrobial prophylaxis did not alter that risk. This study has demonstrated that the use of antimicrobials does not prevent UTI after UDS. Patients with T6 traumatic SCI or abo...Continue Reading

References

Jan 1, 1982·American Journal of Epidemiology·S Lemeshow, D W Hosmer
Sep 1, 1994·The Journal of Hospital Infection·R O DarouicheJ Markowski
Feb 15, 2002·Lancet·John W McDonald, Cristina Sadowsky
Apr 12, 2002·Neurourology and Urodynamics·Werner SchäferUNKNOWN International Continence Society

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Citations

Jun 12, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Michael S Floyd, Rauf N Khadr
Jun 12, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Marcello Torres da SilvaPaulo Sergio Siebra Beraldo
Jun 16, 2021·Annals of Rehabilitation Medicine·EunYoung KimBum-Suk Lee

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